Splenic malignant mesenchymoma in a dog - immunophenotypic features and clinicopathological ramifications: a case report

Dokic, Z.; Pirog, W.; Benák, J.; Lorinson, D.

doi:10.17221/7247-vetmed

Cited by 1 publication

(1 citation statement)

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“…Anesthetic monitoring was carried out by means of temperature control, capnography, pulse oximetry, and electrocardiography. Antibiotic therapy consisting of enrofloxacin g (5 mg/kg, IV) and amoxicillin-clavulanic acid h (8.75 mg/kg, SC) was administered to continue the initial preoperative therapy approved by the attending veterinarian [ 9 , 10 ]. Intraoperatively, a single dose of ampicillin i (40 mg/kg, IV) was administered to overcome the septic condition [ 9 ].…”

Section: Case Presentationmentioning

confidence: 99%

A rare case of splenic abscess with septic peritonitis in a German shepherd dog

et al. 2014

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BackgroundSplenic abscess is a rare disease with only few reports in small-animal practice as well as in human medicine. It has been mostly reported in immunocompromised patients or following penetrating foreign bodies. This report aims to add to the current veterinary literature on recommended diagnostic tools for splenic abscess, as well as to provide follow-up findings after successful surgical treatment.Case presentationAn 8-year-old male German shepherd dog was admitted to the clinic for evaluation of fever, anorexia, and lethargy for the previous 3 days. During the physical examination, a mass was palpated in the left cranioventral abdomen. Diagnostic imaging including radiography and ultrasonography revealed the presence of a large mass in the spleen and signs of peritonitis. Laboratory tests reflected highly septic pyogranulomatous inflammation and, together with imaging findings, raised a high suspicion of splenic abscess and septic peritonitis. Therapy included complete splenectomy and placement of peritoneal drainage. Bacteriological examination revealed severe infection with Staphylococcus epidermidis and S. pseudintermedius. Histopathological evaluation of the mass confirmed the diagnosis of splenic abscess.ConclusionEarly diagnosis of splenic abscess in small animals requires a high level of suspicion based on clinical and ultrasonographic findings. Immediate surgical intervention is preferable and confirms the diagnosis. Total splenectomy remains the most effective therapy. Although there are many predisposing factors for splenic abscess, the true etiology remains obscure.

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Section: Case Presentationmentioning

confidence: 99%