Fine-needle aspiration of spindle cell and mesenchymal lesions of the salivary glands

Chhieng, David C.; Cohen, Jean‐Marc; Cangiarella, Joan

doi:10.1002/1097-0339(200010)23:4<253::aid-dc8>3.0.co;2-0

Cited by 44 publications

(35 citation statements)

References 20 publications

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“…The tumor cells were weakly positive for S-100 but negative for HMB-45. [13][14][15][16][17] In our series, the degree of cellularity of the smears was significantly lower in the cases with primary DM compared with those with primary non-DM (P = .003). In our experience with melanomas in general, paucity of cellular material can be a significant cause of an unsatisfactory procedure.…”

Section: Ztable 3z Cytopathologic Features Of Recurrent/metastatic Tumentioning

confidence: 67%

“…[13][14][15][16][17] The reports describe variably sized groups of spindle cells, sometimes with a fascicular arrangement, with focal areas of cellular dissociation. The cells exhibit mild to moderate cytologic zImage 5z Smear of metastatic tumor in a patient with primary "combined" desmoplastic melanoma.…”

Section: Discussionmentioning

confidence: 99%

“…[9][10][11][12] The cytologic features of DM have been infrequently reported in the literature; to our knowledge, only 5 cases have been described, as single cases in large series of metastatic tumors or as isolated case reports. [13][14][15][16][17] The aims of this study were to document the cytopathologic features of metastatic and recurrent melanoma in a large series of patients from the Sydney Melanoma Unit (SMU), Sydney, Australia, with histologically confirmed primary cutaneous DM and to compare them with the features of metastatic and recurrent lesions in patients with non-DMs.…”

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confidence: 99%

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Cytologic Features of Metastatic and Recurrent Melanoma in Patients with Primary Cutaneous Desmoplastic Melanoma

et al. 2008

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Desmoplastic melanoma (DM) is a rare subtype of melanoma characterized by malignant spindle cells associated with prominent fibrocollagenous stroma. Primary melanomas may be entirely desmoplastic ("pure" DM) or exhibit a desmoplastic component admixed with a nondesmoplastic component ("combined" DM). The cytologic features of only 5 cases of DM have been reported previously. Fine-needle biopsy (FNB) specimens from 20 recurrent or metastatic lesions in patients with cutaneous DM and 20 recurrent or metastatic lesions from patients with primary cutaneous non-DM were examined and compared. FNB specimens of patients with DM were less cellular (P = .009) and less often exhibited intranuclear cytoplasmic invaginations (P = .008) and mitotic figures (P = .006) than specimens from patients with non-DM. "Combined" DMs were more commonly composed of epithelioid cells (P = .017) and less often contained bizarre/giant tumor cells (P = .010) than did "pure" DMs. Recurrent and metastatic DM has a range of cytologic appearances. Awareness of the cytologic features and careful clinicopathologic correlation will assist in accurate FNB diagnosis.

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Section: Ztable 3z Cytopathologic Features Of Recurrent/metastatic Tumentioning

confidence: 67%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Cytologic Features of Metastatic and Recurrent Melanoma in Patients with Primary Cutaneous Desmoplastic Melanoma

et al. 2008

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“…[27] Aspiration smears of nodular fasciitis will be highly cellular and have metachromatic myxoid background. [8] The cells are mainly myofibroblasts with plump spindle-shaped/stellate cells having pale, bland, evenly distributed chromatin and prominent nucleoli. However, SFTs have monotonous spindly cells without myxoid background.…”

Section: Discussionmentioning

confidence: 99%

“…Smears from benign peripheral nerve sheath tumors such as schwannoma contain clusters of spindle cells in interlacing bundles against myxoid background. [8] The diagnostic verocay bodies may be present.…”

Section: Discussionmentioning

confidence: 99%

Fine needle aspiration cytology of solitary fibrous tumor of the orbit

Krishnamurthy

Satish

Asha

et al. 2017

J Cytol

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Solitary fibrous tumor (SFT) is a distinct and a rare spindle cell neoplasm, commonly known to occur in the pleura and other serosal sites. With the advent of immunohistochemistry, varied extraserosal sites are being recognized as common locations for this rare tumor. We report a case of SFT in a 50-year-old male patient who presented with multiple swellings in the eyelid, with emphasis on the cytological features.

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Spectrum of head and neck lesions diagnosed by fine-needle aspiration cytology in the pediatric population

Rapkiewicz

Simsir

et al. 2007

Cancer

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Fine-needle aspiration cytology (FNAC) of the head and neck region is well accepted as a diagnostic procedure in the adult population. FNAC in the pediatric population is gaining acceptance as clinicians add this technique to the diagnostic armamentarium. An experience with FNAC of the head and neck region in the pediatric population is described from 2 large inner-city hospitals. Eighty-five cases were retrieved from patients age <18 years. In 52 cases, clinical or surgical follow-up was obtained and among these cases the specificity and sensitivity of FNA was 93% and 100%, respectively. The high specificity of FNAC allows the clinician to be confident of malignancy in a clinically suspicious lesion of the head and neck in a pediatric patient. Cancer

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Fine-needle aspiration of spindle cell and mesenchymal lesions of the salivary glands

Cited by 44 publications

References 20 publications

Cytologic Features of Metastatic and Recurrent Melanoma in Patients with Primary Cutaneous Desmoplastic Melanoma

Cytologic Features of Metastatic and Recurrent Melanoma in Patients with Primary Cutaneous Desmoplastic Melanoma

Fine needle aspiration cytology of solitary fibrous tumor of the orbit

Spectrum of head and neck lesions diagnosed by fine-needle aspiration cytology in the pediatric population

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