Solitary fibrous tumor (SFT) is a distinct and a rare spindle cell neoplasm, commonly known to occur in the pleura and other serosal sites. With the advent of immunohistochemistry, varied extraserosal sites are being recognized as common locations for this rare tumor. We report a case of SFT in a 50-year-old male patient who presented with multiple swellings in the eyelid, with emphasis on the cytological features.
Neuromuscular and vascular hamartoma (NMVH) is a rare lesion arising chiefly in the small intestine. As it shares many of the histological features with other commonly occurring stricturous conditions of the small bowel, there is an ongoing debate whether it is truly hamartomatous or represents just a reactive condition. We are reporting a case of NMVH in the terminal ileum in a 32-year-old male who presented with symptoms of intestinal obstruction.
AIM:Coagulation tests are often requested as urgent tests by the intensive care clinicians. This is one of the many tests which is grossly influenced by pre analytical errors. Platelet contains phospholipids and pro coagulants which can interfere with the coagulation results. Preparation of platelet poor plasma by centrifuging at 1500 g for 15 mins is the standard recommended procedure. In order to decrease the turnaround time, several authors have centrifuged the sample at high speeds to obtain platelet poor plasma and reported unaffected coagulation test results. However, the effect of platelet contamination on the results of the coagulation tests was less well studied. METHODS: We prospectively analysed the coagulation test results after centrifuging at 1000 g (Standard spin) and 500 g (Intervention spin) respectively. A total of 31 samples were studied out of which, 15 had normal coagulation and 16 had abnormal coagulation results. Agreement of values between the two preparations were determined with Bland Altman analysis. RESULTS: Median platelet count in standard spin group was 4000/cumm and with intervention spin was 25000/cumm. Estimated mean difference (95% CI) between intervention and standard spin for prothrombin time was -0.59 secs (-0.96 to -0.03), for INR was -0.059 (-0.11 to -0.001) and for activated partial thromboplastin time was -0.59 secs (-1.5 to +0.3). CONCLUSIONS: Platelet contamination of plasma insignificantly shorten the coagulation test results and remains clinically useful.
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