Fine Needle Aspiration Cytology of Primary Lymphoid Lesions of the Orbit

Subramanian, Rajiv; Solo, Seyiechutuo; Mishra, Manisha Manaswini; Murugan, Paari; Siddaraju, Neelaiah; Basu, Debdatta; Srinivasan, Renuka

doi:10.1159/000325757

Cited by 9 publications

(4 citation statements)

References 7 publications

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“…An increase in mast cells perhaps aids in the diagnosis of low-grade NHL of small lymphocytic/lymphoplasmacytic morphology. 24,25 An infected/ulcerated mucocele was the only inflammatory lesion in the eyelid group; cytologically, this was interpreted as a suppurative lesion. Although the cytologic diagnosis was justified in this case, review of cytologic smears revealed the presence of mucinous material indicative of an infected mucocele.…”

Section: Inflammatory and Infectious Lesionsmentioning

confidence: 99%

Use of Fine Needle Cytology in the Diagnosis of Orbital and Eyelid Mass Lesions

Solo

Siddaraju²,

Srinivasan³

2009

Acta Cytologica

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Section: Inflammatory and Infectious Lesionsmentioning

confidence: 99%

Use of Fine Needle Cytology in the Diagnosis of Orbital and Eyelid Mass Lesions

Solo

Siddaraju²,

Srinivasan³

2009

Acta Cytologica

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“…Distinguishing them as benign or malignant lesions is always a diagnostic challenge. Primary orbital lymphoid lesions are categorised into three groups: idiopathic inflammation/inflammatory pseudotumor, reactive lymphoid hyperplasia/pseudolymphoma, and malignant lymphoma [2].…”

Section: Discussionmentioning

confidence: 99%

Proptosis under evaluation—a rare case report on pseudolymphoma of orbit

Raguraman

Kushwaha

Penubarthi

2023

Egypt J Otolaryngol

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Background Orbital pseudolymphoma is one of the rare diseases affecting the ocular adnexa and causing various symptoms requiring histopathological evidence for diagnosis and appropriate treatment with oral steroids or immunosuppressive agents. However, there is less literature available on this disease, thus adding to it will help in the early diagnosis and treatment of the patients. Case presentation A 48-year-old female from a village in South India came to our tertiary care centre with the only complaints of right eye protrusion for 1 year. With a working diagnosis of intraorbital mass, radiological investigations like contrast-enhanced CT and MRI were taken. It showed well-capsulated mass involving the right inferior rectus extending into the intraconal space just abutting the optic nerve. Trans-antral endoscopic biopsy under general anaesthesia was taken and reported as pseudolymphoma proven with CD 3 and CD 20 immunohistochemistry markers. The patient was treated with oral corticosteroids and tapered over a period of 3 months. During the treatment period, the patient developed no diminution of vision or new complaints. Conclusion Orbital pseudolymphomas are benign lymphoproliferative diseases affecting the ocular adnexal tissue. Patients can present with painless ptosis, proptosis, diplopia, or eyelid swelling. Prompt diagnosis and treatment result in the remission of the disease.

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“…Both the primary neoplasms were NHL B‐cell type. The orbit is a common location for lymphoid lesions, despite being devoid of lymphoid tissue 10. Most of the lymphomas seen in the orbit are of B‐cell type and the frequency ranges from 39.5% to 88.1%.…”

Section: Discussionmentioning

confidence: 99%

FNA in diagnosis of orbital lesions causing proptosis in adults

Singhal

Mundi

Handa

et al. 2011

Diagnostic Cytopathology

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The orbit is affected by a wide range of pathologic lesions, for which a morphologic diagnosis is needed to allow adequate therapy. With increasing use of fine needle aspiration (FNA) in diagnostic pathology, the procedure has been applied for the diagnosis of space occupying lesions of the orbit. We present the cytomorphological diagnosis on orbital FNA in adult patients presenting with proptosis. Records of seven adult patients who had presented with proptosis and had undergone orbital FNA were retrieved and analysed. FNA was performed from the palpable mass in six cases and under ultrasound guidance in one case. No complication during or after FNA was reported in any of the cases. Histopathological diagnosis was available in 5 cases. Out of the 7 cases, 3 were non-neoplastic (2 inflammatory lesions, 1 reactive lymphoid hyperplasia) and 4 were neoplastic (2 primary tumors and 2 secondary involvement). Both the primary tumors were non Hodgkin's lymphoma (NHL) B-cell type. Metastases included one case of uterine sarcomatoid carcinoma and one case of secondary involvement by extension of olfactory neuroblastoma. In all the neoplastic cases, cytological diagnosis corresponded with the histopathological diagnosis. It can be concluded that cause of proptosis among adults are different from those among children and include secondary malignancies. FNA is a simple and important preliminary diagnostic modality in the assessment of adult proptosis prior to any surgical intervention.

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Fine Needle Aspiration Cytology of Primary Lymphoid Lesions of the Orbit

Cited by 9 publications

References 7 publications

Use of Fine Needle Cytology in the Diagnosis of Orbital and Eyelid Mass Lesions

Use of Fine Needle Cytology in the Diagnosis of Orbital and Eyelid Mass Lesions

Proptosis under evaluation—a rare case report on pseudolymphoma of orbit

FNA in diagnosis of orbital lesions causing proptosis in adults

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