Fibrosarcoma in a Père David's Deer

Hubbard, G. Baker; Fletcher, K. C.; Schmidt, R. E.

doi:10.1177/030098588302000616

Cited by 6 publications

(15 citation statements)

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“…2 Mammary neoplasias have not been reported in wild deer, and they are rare in other ruminants. 1,5 In this case, the neoplasia behaved aggressively as seen in mammary neoplasias in other species.…”

mentioning

confidence: 99%

Metastatic Adenocarcinoma of the Mammary Gland in a Père David's Deer

Veatch

Carpenter

1993

J VET Diagn Invest

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mentioning

confidence: 99%

Metastatic Adenocarcinoma of the Mammary Gland in a Père David's Deer

Veatch

Carpenter

1993

J VET Diagn Invest

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“…R. Soc. B 370: 20140224 cutaneous sites in an animal as well as in the lungs [7,8,113], where they have been interpreted as metastatic by some investigators [7,8,114].…”

Section: (C) Associations Between Benign and Malignant Neoplasiasmentioning

confidence: 99%

“…Evidence from captive, undomesticated animals, primarily in zoo populations, suggests that cancer may be responsible for about 1-5% of deaths [6][7][8][9]. But exposure to oncogenic agents and mortality from other causes likely differs between wild, captive and domestic populations.…”

Section: Introduction To Pervasiveness Of Cancer: Evolutionary Considmentioning

confidence: 99%

“…Cancer could be difficult to find in nature for several reasons: a low frequency of oncogenic development to malignancy, short survival after malignancy and reduced survival prior to malignancy [4,5]. Evidence from captive, undomesticated animals, primarily in zoo populations, suggests that cancer may be responsible for about 1-5% of deaths [6][7][8][9]. But exposure to oncogenic agents and mortality from other causes likely differs between wild, captive and domestic populations.…”

Section: Introduction To Pervasiveness Of Cancer: Evolutionary Considerationsmentioning

confidence: 99%

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Infection and cancer in multicellular organisms

Ewald

2015

Phil. Trans. R. Soc. B

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Evolutionary considerations suggest that oncogenic infections should be pervasive among animal species. Infection-associated cancers are well documented in humans and domestic animals, less commonly reported in undomesticated captive animals, and rarely documented in nature. In this paper, we review the literature associating infectious agents with cancer to evaluate the reasons for this pattern. Non-malignant infectious neoplasms occur pervasively in multicellular life, but oncogenic progression to malignancy is often uncertain. Evidence from humans and domestic animals shows that non-malignant infectious neoplasms can develop into cancer, although generally with low frequency. Malignant neoplasms could be difficult to find in nature because of a low frequency of oncogenic transformation, short survival after malignancy and reduced survival prior to malignancy. Moreover, the evaluation of malignancy can be ambiguous in nature, because criteria for malignancy may be difficult to apply consistently across species. The information available in the literature therefore does not allow for a definitive assessment of the pervasiveness of infectious cancers in nature, but the presence of infectious neoplasias and knowledge about the progression of benign neoplasias to cancer is consistent with a widespread but largely undetected occurrence.

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“…15 A uterine adenocarcinoma in a sika deer ( Cervus nippon ) 22 was also documented. Additionally, fibrosarcoma, 12 mammary adenocarcinoma, 26 concurrent multicentric hemangiosarcoma, and ovarian teratoma 27 have been described in the Pere David’s deer ( Elaphurus davidianus ). However, ovarian tumors of epithelial origin have not yet been reported in deer, and such tumors are rare in both ruminants and other species.…”

mentioning

confidence: 99%