Fibromatosis and fibrosarcoma following irradiation therapy

Pettit, Vernon D.; Chamness, James T.; Ackerman, Lauren V.

doi:10.1002/1097-0142(195401)7:1<149::aid-cncr2820070116>3.0.co;2-x

Cited by 81 publications

(6 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hutchinson et al [10] successfully treated a patient with pelvic fibromatosis using chemotherapy. This is contradictory to Petit et al [13], who reported an inductive effect of radiation on the development of fibromatoses as early as 1954. This is contradictory to Petit et al [13], who reported an inductive effect of radiation on the development of fibromatoses as early as 1954.…”

contrasting

confidence: 64%

Fibromatosis ? a rare retroperitoneal tumour

Uranüs

Beham

Stenzl

1990

Langenbecks Arch Chir

View full text Add to dashboard Cite

A case of retroperitoneal fibromatosis in a 28-year-old white male is presented. The soft tissue tumor, with a weight of 8000 g, was resected by laparotomy. Because of adhesions to the ascending colon and the right ureter, a hemicolectomy and partial resection of the right ureter had to be performed additionally. Intraabdominal fibromatoses are very infrequent tumorous lesions of the connective tissue, occurring retroperitoneally only in isolated cases. Their etiology is presumed to be a hereditary or gene-associated defect in the regulation of connective tissue growth. In addition, trauma and hormonal influences often appear as inductive cofactors.

show abstract

contrasting

confidence: 64%

Fibromatosis ? a rare retroperitoneal tumour

Uranüs

Beham

Stenzl

1990

Langenbecks Arch Chir

View full text Add to dashboard Cite

show abstract

“…This treatment may possibly stop the extension and growth of the tumour, but Rock et al reported in their large series that success rates were low with radiation as the only treatment, and 69% of their patients required further therapy [21]. Malignant transformation of EADTs has also been reported after radiation therapy [20] which must be limited to the cases in which it is not possible to eradicate the tumour with an extensive operation.…”

Section: Discussionmentioning

confidence: 99%

“…Chemotherapy [18], radiation therapy [11,23], hormonal blocking agents [12], cholchicine [6], and both wide resection and radical ablation [5,7,10,13,21] [20,21]. Wide local excision is the most successful treatment even in recurrent cases.…”

Section: Introductionmentioning

confidence: 99%

Surgical treatment of extra-abdominal desmoid tumours (aggressive fibromatoses)

Higaki

Tateishi

Ohno

et al. 1995

International Orthopaedics

View full text Add to dashboard Cite

Extra-abdominal desmoid tumours (EADT) are benign lesions but difficult to cure because of their infiltrative nature and tendency to recur. Among many treatments recommended in the past, wide excision has been successful, even in difficult cases. We have analyzed retrospectively 41 cases of histologically confirmed EADTs. A total of 98 operations were performed on these patients: 29 wide excisions on 22 patients, 52 intra-lesional excisions with wide margins on 16 patients, and 17 incomplete excisions on 3 patients. One patient, with intra-pelvic lesions, died of a massive haemorrhage 3 days after surgery. Forty patients were followed from between 3 and 29 years. One, who had a multicentric EADT for 21 years, died from the disease. The significant factors concerning local recurrence after wide procedures were an unsatisfactory initial wide local excision, disease affecting 4 or more muscles and the invasive nature of the recurrences. We recommend wide local excision of these tumours in all anatomical areas that allow this procedure. When major nerves and vessels are involved, we recommend an intralesional excision with wide margins in order to preserve limb function. Radiation therapy should be confined to cases in which wide local procedures are not feasible. Overall, 37 of our patients (90%) were cured of the disease, 2 had their disease controlled, and 2 died.

show abstract

“…Although our case showed increased cellularity, it might be distinguished from the usual voluminous fibrosarcomas by uncommonness of pleomorphism, mitotic figures and areas of necrosis. The more prominetit cellularity and giant cells in the excision sections could be attributed to the X-ray irradiation, but our case might be differentiated from the fibromatosis or fibrosarcoma following irradiation therapy (Pettit et al 1954).…”

Section: Discussionmentioning

confidence: 60%

Fibrous tumor of infancy — Report of a case originating in the oral cavity

Takagi

Ishikawa

1973

J Oral Pathology Medicine

View full text Add to dashboard Cite

Abstract. A fibrous tumor of infancy of the floor of the mouth is reported. The tumor was characterized by congenital occurrence, deeply infiltrating, dense immature fibroblastic cells, focal chondroid differentiation, rapid new growth 3 years following irradiation and no recurrence 6 years after incomplete excision. The diagnosis of an aggressive infantile fibromatosis or juvenile fibromatosis, differentiated fibrosarcoma type, was considered to be the most acceptable.

show abstract

Fibromatosis and fibrosarcoma following irradiation therapy

Cited by 81 publications

References 14 publications

Fibromatosis ? a rare retroperitoneal tumour

Fibromatosis ? a rare retroperitoneal tumour

Surgical treatment of extra-abdominal desmoid tumours (aggressive fibromatoses)

Fibrous tumor of infancy — Report of a case originating in the oral cavity

Contact Info

Product

Resources

About