Fibromatosis ? a rare retroperitoneal tumour

Abstract

A case of retroperitoneal fibromatosis in a 28-year-old white male is presented. The soft tissue tumor, with a weight of 8000 g, was resected by laparotomy. Because of adhesions to the ascending colon and the right ureter, a hemicolectomy and partial resection of the right ureter had to be performed additionally. Intraabdominal fibromatoses are very infrequent tumorous lesions of the connective tissue, occurring retroperitoneally only in isolated cases. Their etiology is presumed to be a hereditary or gene-associated defect in the regulation of connective tissue growth. In addition, trauma and hormonal influences often appear as inductive cofactors.

Non‐malignant fibroblastic/myofibroblastic tumors in pediatric age group: Clues and pitfalls to the cytological diagnosis

“…Commonly they present as a firm, nontender mass and show variable aetiology. Trauma, genetic factors, tissue injury in a person having genetic predisposition to excessive fibroblastic growth, altered production of extracellular matrix and hormonal disorders are some of the factors listed as aetiological agents . The clinical management in these tumours is usually surgical excision; however, some of these lesions have been seen to be associated with spontaneous regression while others have shown frequent recurrences post incomplete excision .…”

“…All these lesions are composed of proliferating fibrous tissue on pathological examination.Commonly they present as a firm, nontender mass and show variable aetiology. Trauma, genetic factors, tissue injury in a person having genetic predisposition to excessive fibroblastic growth, altered production of extracellular matrix and hormonal disorders are some of the factors listed as aetiological agents 2,5,6. The clinical management in these tumours is usually surgical excision; however, some of these lesions have been seen to be associated with spon-taneous regression 7 while others have shown frequent recurrences F I G U R E 2 (A & B) Fine needle aspiration cytology smears from lipofibromatosis showing admixture of mature adipose tissue, benign fibrous component and skeletal muscle fibre (red arrow) [Giemsa, 10x] [inset showing high power view of mature adipose tissue admixed with many singly scattered plump to spindle shaped cells (A) and skeletal muscle fibre (B) (Giemsa, 40x)] (C &D) Fibromatosis colli.…”