Fertilization after standard in vitro fertilization versus intracytoplasmic sperm injection in subfertile males using sibling oocytes

Pisarska, Margareta D.; Casson, Peter R.; Cisneros, Pauline; Lamb, Dolores J.; Lipshultz, Larry I.; Buster, John E.; Carson, Sandra Ann

doi:10.1016/s0015-0282(98)00538-x

Cited by 58 publications

(38 citation statements)

References 17 publications

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“…Thus, after controlling for possible paternal and maternal effects, we demonstrated that embryo quality does not seem to be influenced by the mode of fertilization (IVF or ICSI). This finding confirms the assumptions raised by others [3,[8][9][10][11][12][13]. We conclude that embryo quality depends on intrinsic factors of the gametes involved rather than on the fertilization process per se.…”

Section: Discussionsupporting

confidence: 93%

“…Similar results were demonstrated by Hsu et al [6] and Frattarelli et al [7]. Others, however, found embryo quality to be comparable between the two methods [3,[8][9][10][11][12][13], or even superior in ICSI [2,14,15].…”

Section: Introductionsupporting

confidence: 83%

“…Verheyen and his colleagues demonstrated similar results in 20 couples with relative male factor infertility (failed fertilization rates of 0 vs. 50%) [11]. Piskara et al [9], Staessen et al [10] and Khamsi et al [15] demonstrated a similar trend towards lower rates of total fertilization failure in ICSI than IVF. Reported rates ranged between 10 to 27.8% for IVF vs. 0-5.5% for ICSI.…”

Section: Discussionmentioning

confidence: 75%

“…The strength of this study lies in the comparison of the rate of high-quality embryos per couple between IVF and ICSI, which was performed in only one previous sibling oocyte study in the literature [9]. The results demonstrated no significant differences between the IVF and ICSI groups (for the whole study sample) in the rate of high-quality embryos (grade A or grade A 1 ).…”

Section: Discussionmentioning

confidence: 86%

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Comparison of embryo quality between intracytoplasmic sperm injection and in vitro fertilization in sibling oocytes

Yoeli

Orvieto

Ashkenazi

et al. 2008

J Assist Reprod Genet

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Background The aim of the present study was to compare the quality of embryos derived from sibling oocytes by in vitro fertilization (IVF) or ICSI. Methods Consecutive patients with a less than 40% fertilization rate in a previous standard IVF cycle or with relative male factor infertility were recruited for the study. The oocytes retrieved from each patient were divided into two groups for either conventional insemination (group A) or ICSI (group B). Power analysis showed that to detect a 25% difference in the rate of high-quality embryos between the groups with a power of 0.8, at least 1,200 oocytes were needed in each group. Results One hundred seventy-seven patients were included in the study. Group A was comprised of 1,526 oocytes and group B of 1,480 sibling oocytes. As expected, the fertilization rate was significantly higher in group B than group A (67.1 vs. 43.6%, p < 0.001). No significant between-group differences were observed in cleavage rate (92.7 and 89.7%, respectively) and the rate of either grade A embryos (22.6 and 23.9%, respectively) or grade A 1 embryos (37.3 and 33.5%, respectively).However, in the subgroup of patients with relative malefactor infertility (n=36), the rate of grade A 1 embryos was significantly higher in the IVF than the ICSI group (46.4 vs. 29.0%, respectively, p=0.02). Conclusions Embryo quality does not seem to be influenced by the mode of fertilization (IVF or ICSI). We assume that embryo quality depends on intrinsic factors of the gametes involved rather than on the fertilization process per se.

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Section: Discussionsupporting

confidence: 93%

Section: Introductionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 75%

Section: Discussionmentioning

confidence: 86%

See 2 more Smart Citations

Comparison of embryo quality between intracytoplasmic sperm injection and in vitro fertilization in sibling oocytes

Yoeli

Orvieto

Ashkenazi

et al. 2008

J Assist Reprod Genet

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“…This approach is often recommended despite the data that shows that fertilization rate and treatment outcome should be comparable with IVF and ICSI when the semen parameters are in the normal range and ICSI improves fertilization rates only when the semen parameters are borderline or when the morphology is poor [19][20][21][22]. Several studies have reported lower fertilization rates with IVF versus ICSI and a higher risk for complete fertilization failure with IVF among couples with unexplained infertility undergoing IVF following failed IUIs [15][16][17][18]23].…”

Section: Discussionmentioning

confidence: 99%

The role of hyaluronic acid binding assay in choosing the fertilization method for patients undergoing IVF for unexplained infertility

Kovács

Kováts

Sajgo

et al. 2010

J Assist Reprod Genet

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Purpose Patients with unexplained infertility may have fertilization problems. Split fertilization (ICSI and conventional IVF on sibling oocytes) is often used to avoid poor fertilization. Our aim was to assess the ability of hyaluronic acid binding (HA-binding) assay to predict spontaneous fertilization during IVF. Methods Prospective, blinded, controlled trial. Patients undergoing their first IVF cycle for unexplained infertility were eligible. Split fertilization was used. IVF and ICSI fertilization rates and embryo development based on 3 HAbinding cut-offs (< 60%; 60-80%; >80%) were compared. Results ICSI fertilization was higher than IVF, but none of the HA-binding cut-off levels predicted those cases where IVF was less effective, therefore ICSI only would have lead to improved outcome. Embryo development and morphology were similar in all cut-off groups. Conclusions HA-binding did not predict spontaneous fertilization in patients with unexplained infertility undergoing IVF treatment. When it was used for "screening" it did not help to select the method of fertilization.

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Assisted reproductive technologies for male subfertility

Cissen

Bensdorp

Cohlen

et al. 2016

Cochrane Database of Systematic Reviews

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Fertilization after standard in vitro fertilization versus intracytoplasmic sperm injection in subfertile males using sibling oocytes

Cited by 58 publications

References 17 publications

Comparison of embryo quality between intracytoplasmic sperm injection and in vitro fertilization in sibling oocytes

Comparison of embryo quality between intracytoplasmic sperm injection and in vitro fertilization in sibling oocytes

The role of hyaluronic acid binding assay in choosing the fertilization method for patients undergoing IVF for unexplained infertility

Assisted reproductive technologies for male subfertility

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