“…In the quality assessment of the 21 RCTs, 10 were rated A, 49,52,54,64,69,70,73,76,79,81 six were rated B, 51,55,56,67,71,75 three were rated C, 48,72,78 and two were rated D. 57,58 Of the 14 observational studies, two were rated B, 50,63 three were rated C, 53,61,62 eight were rated D, 59,60,66,68,74,77,80,82 and one was rated E. 65 …”