Feasibility and functional correlates of left atrial volume changes during stress echocardiography in chronic coronary syndromes

Morrone, Doralisa; Arbucci, Rosina; Wierzbowska−Drabik, Karina; Ciampi, Quirino; Peteiro, Jesús; Ágoston, Gergely; Varga, Albert; Camarozano, Ana Cristina; Boshchenko, Alla A.; Ryabova, Tamara; Dekleva, Milica; Симова, Яна; Haber, Diego M. Lowenstein; Tešić, Milorad; Bošković, Nikola; Djordjevic‐Dikic, Ana; Beleslin, Branko; DʼAlfonso, Maria Grazia; Mori, Fabio; Rodríguez‐Zanella, Hugo; Kasprzak, Jarosław D.; Cortigiani, Lauro; Lattanzi, Fabio; Scali, Maria Chiara; Torres, Marco Antônio Rodrigues; Daros, Clarissa Borguezan; Pretto, José Luis de Castro e Silva; Gaibazzi, Nicola; Zagatina, Angela; Zhuravskaya, Nadezhda; Amor, Miguel; Mieles, Paul E Vargas; Merlo, Pablo; Monte, Ines; D’Andrea, Antonello; Re, Federica; Salvo, Giovanni Di; Merli, E; Lorenzoni, Valentina; Nes, Michele De; Paterni, Marco; Limongelli, Giuseppe; Prota, Costantina; Citro, Rodolfo; Colonna, Paolo; Villari, Bruno; Antonini‐Canterin, Francesco; Carpeggiani, Clara; Lowenstein, Jorge

doi:10.1007/s10554-020-02071-5

Cited by 9 publications

(4 citation statements)

References 31 publications

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“…Based on previously reported lower limits of reference values, we considered an abnormal LAVI value ≥ 34 mL/m 2 and an abnormal LASr value < 24% [ 18 ]. Previous studies have shown that the normal stress response is characterized by a reduction or mild increase in LAVI during stress, with an increase of LASr [ 19 , 20 , 21 ].…”

Section: Methodsmentioning

confidence: 99%

Rest and Stress Left Atrial Dysfunction in Patients with Atrial Fibrillation

Zagatina,

Rivadeneira Ruiz,

Ciampi

et al. 2023

JCM

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Background: Left atrial (LA) myopathy with paroxysmal and permanent atrial fibrillation (AF) is frequent in chronic coronary syndromes (CCS) but sometimes occult at rest and elicited by stress. Aim: This study sought to assess LA volume and function at rest and during stress across the spectrum of AF. Methods: In a prospective, multicenter, observational study design, we enrolled 3042 patients [age = 64 ± 12; 63.8% male] with known or suspected CCS: 2749 were in sinus rhythm (SR, Group 1); 191 in SR with a history of paroxysmal AF (Group 2); and 102 were in permanent AF (Group 3). All patients underwent stress echocardiography (SE). We measured left atrial volume index (LAVI) in all patients and LA Strain reservoir phase (LASr) in a subset of 486 patients. Results: LAVI increased from Group 1 to 3, both at rest (Group 1 = 27.6 ± 12.2, Group 2 = 31.6 ± 12.9, Group 3 = 43.3 ± 19.7 mL/m2, p < 0.001) and at peak stress (Group 1 = 26.2 ± 12.0, Group 2 = 31.2 ± 12.2, Group 3 = 43.9 ± 19.4 mL/m2, p < 0.001). LASr progressively decreased from Group 1 to 3, both at rest (Group 1 = 26.0 ± 8.5%, Group 2 = 23.2 ± 11.2%, Group 3 = 8.5 ± 6.5%, p < 0.001) and at peak stress (Group 1 = 26.9 ± 10.1, Group 2 = 23.8 ± 11.0 Group 3 = 10.7 ± 8.1%, p < 0.001). Stress B-lines (≥2) were more frequent in AF (Group 1 = 29.7% vs. Group 2 = 35.5% vs. Group 3 = 57.4%, p < 0.001). Inducible ischemia was less frequent in SR (Group 1 = 16.1% vs. Group 2 = 24.7% vs. Group 3 = 24.5%, p = 0.001). Conclusions: In CCS, rest and stress LA dilation and reservoir dysfunction are often present in paroxysmal and, more so, in permanent AF and are associated with more frequent inducible ischemia and pulmonary congestion during stress.

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Section: Methodsmentioning

confidence: 99%

Rest and Stress Left Atrial Dysfunction in Patients with Atrial Fibrillation

Zagatina,

Rivadeneira Ruiz,

Ciampi

et al. 2023

JCM

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“…Although its strengths and potentiality, SE has important weaknesses: the operator-dependence can be minimized, but not abolished, and regional wall motion abnormalities are not helpful to identify factors that are not linked to a coronary stenosis, while the introduction of medical therapy resulted in a reduction of positive tests in the last decades [42].…”

Section: Stress Echocardiography As a Multiparametric Testmentioning

confidence: 99%

Perspectives in noninvasive imaging for chronic coronary syndromes

Morrone

Gentile

Aimo

et al. 2022

International Journal of Cardiology

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“…Emerging data suggest left atrial mechanics may play a significant role in proportion of patients with heart failure with preserved ejection fraction, particularly in those with atrial dysrhythmias. While left atrial volume index at rest may convey risk of heart failure with preserved ejection fraction, changes in left atrial volume with stress may better risk stratify patients with 1 out of 5 patients seeing a reduction in left atrial volume with stress, but another 1 out of 5 with normal left atrial size dilating during stress [25]. Left atrial strain, particularly reservoir strain is also feasible, reproducible, and important to characterize left atrial function during stress.…”

Section: Abcde-stress Echo In Diastolic Heartmentioning

confidence: 99%

Stress Echo 2030: The Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging

Ciampi

Cortigiani²,

Arruda‐Olson

et al. 2021

JCM

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With stress echo (SE) 2020 study, a new standard of practice in stress imaging was developed and disseminated: the ABCDE protocol for functional testing within and beyond CAD. ABCDE protocol was the fruit of SE 2020, and is the seed of SE 2030, which is articulated in 12 projects: 1-SE in coronary artery disease (SECAD); 2-SE in diastolic heart failure (SEDIA); 3-SE in hypertrophic cardiomyopathy (SEHCA); 4-SE post-chest radiotherapy and chemotherapy (SERA); 5-Artificial intelligence SE evaluation (AI-SEE); 6-Environmental stress echocardiography and air pollution (ESTER); 7-SE in repaired Tetralogy of Fallot (SETOF) ; 8-SE in post-COVID-19 (SECOV); 9: Recovery by stress echo of conventionally unfit donor good hearts (RESURGE); 10-SE for mitral ischemic regurgitation (SEMIR); 11-SE in valvular heart disease (SEVA); 12-SE for coronary vasospasm (SESPASM). The study aims to recruit in the next 5 years (2021–2025) ≥10,000 patients followed for ≥5 years (up to 2030) from ≥20 quality-controlled laboratories from ≥10 countries. In this COVID-19 era of sustainable health care delivery, SE2030 will provide the evidence to finally recommend SE as the optimal and versatile imaging modality for functional testing anywhere, any time, and in any patient.

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Feasibility and functional correlates of left atrial volume changes during stress echocardiography in chronic coronary syndromes

Cited by 9 publications

References 31 publications

Rest and Stress Left Atrial Dysfunction in Patients with Atrial Fibrillation

Rest and Stress Left Atrial Dysfunction in Patients with Atrial Fibrillation

Perspectives in noninvasive imaging for chronic coronary syndromes

Stress Echo 2030: The Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging

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