Fe-TCPP@CS nanoparticles as photodynamic and photothermal agents for efficient antimicrobial therapy

Abstract

Traditional antibacterial therapies always rely on antibiotics, which have led to the overuse of antibiotics and caused the emergence of multidrug-resistant (MDR) bacteria in recent years. In this study, an...

Effect of Topology on Photodynamic Sterilization of Porphyrinic Metal‐Organic Frameworks

“…The antibacterial performance of MOF‐545 were also compared with that of other TCPP‐containing materials against E. coli (Table S2). MOF‐545 exposed to white LED light (4 mW/cm 2 ) for 20 min can reduce the number of E. coli colonies by 3 log while other TCPP‐containing materials required higher power intensity or longer irradiation time [6d,f,26] . In addition, The MOFs exhibited better photodynamic antibacterial performance for S. aureus than E. coli under the same experimental conditions due to the different cell wall structures of Gram‐negative and Gram‐positive bacteria [5] .…”

Graphene quantum dot-porphyrin/phthalocyanine multifunctional hybrid systems: from interfacial dialogue to application

“…ROS causes random oxidation of DNA, RNA, and/or lipid, leading to bacterial destruction, and thus preventing the development of specific resistance mechanisms in bacteria. 295,297…”

“…ROS causes random oxidation of DNA, RNA, and/or lipid, leading to bacterial destruction, and thus preventing the development of specific resistance mechanisms in bacteria. 295,297 Sen et al recently reported the antibacterial activity of novel ZnPcs (3,4)-containing octa-imines and their nanoconjugates (3@N,S-GQDs and 4@N,S-GQDs) in S. aureus. As the singlet oxygen production increased for 3@N,S-GQDs and 4@N, S-GQDs compared to ZnPcs (3,4) alone, photoactivity resulted in complete cell destruction.…”

Latest trends on photodynamic disinfection of Gram-negative bacteria: photosensitizer’s structure and delivery systems

“…18). The authors showed that the introduction of metal nodes prevented the self-aggregation of the porphyrin and improved 1 O 2 generation [117] . By using both PTT and PDT, the authors reached a 98% of E. coli reduction of bacterial survival, while PTT or PDT only reached 45% and 42%, respectively.…”