Fe(CO)₃ and Rh(acac) complexes of ergosteryl and 7-dehydrocholesteryl acetates: A high field nuclear magnetic resonance study

Abstract

The 500 MHz 1H and 125 MHz 13C spectra of ergosteryl and 7-dehydrocholesteryl acetate were recorded in C6D6 and CDCl3 and assigned using two-dimensional NMR techniques. It is shown that incorporation of an Fe(CO)3 or a Rh(acac) moiety onto the ring B diene system affects the chemical shifts of neighbouring protons and carbons. These changes are discussed in terms of the anisotropic properties of the organometallic fragments.

Highly active and long lived homogeneous catalyst for the dehydrogenation of dimethylamine borane starting with ruthenium(III) acetylacetonate and oleylamine precatalyst

“…The enhancement in the catalytic activity by adding 3 equivalent oleylamine to the precatalyst solution of Ru(acac) 3 [43], and Ru(II)-polypyridyl complexes with five-and six-membered chelate rings [44].…”

Synthesis of Transition-Metal Steroid Derivatives

“…Detailed NMR analysis and reactivity studies of these species were later reported. 297,298 Using Fe(CO) 5 , ergosterol and 7dehydrocholesterol were also, respectively, converted into the corresponding tricarbonyliron-protected compounds 621c and 622b. 299 Likewise, compounds 622a and 623 were later synthesized and fully NMR characterized, and their molecular structures were confirmed by X-ray diffraction studies.…”

“…In the mid 1970s, benzylideneacetone(tricarbonyl)iron was shown to be a better Fe precursor for formation of 621a and its benzoyl analogue 621b , both of which were isolated in good yields (70–71%). Detailed NMR analysis and reactivity studies of these species were later reported. , Using Fe(CO) 5 , ergosterol and 7-dehydrocholesterol were also, respectively, converted into the corresponding tricarbonyliron-protected compounds 621c and 622b . Likewise, compounds 622a and 623 were later synthesized and fully NMR characterized, and their molecular structures were confirmed by X-ray diffraction studies …”