Fatty liver disease, glucose tolerance and insulin resistance in obese adolescents

Abstract

This study provides no support to the notion that intra-hepatic fat has a role in the regulation of fasting blood glucose, 2-h postprandial blood glucose or systemic insulin resistance.

The association among skeletal muscle phosphocreatine recovery, adiposity, and insulin resistance in children

“…Our study participants performed a similar exercise stress of 5 x 30‐s bouts of quadriceps exercise (total exercise time: 2.5 min), however, at a significantly higher percentage of their peak capacity (65% versus 30%). Slyper and colleagues have also revealed that adiposity, visceral fat volume in particular, is the sole predictor of insulin resistance in obese adolescents ; therefore, it clearly remains a challenge to dissociate the relationship between obesity, insulin resistance, and skeletal muscle oxidative capacity.…”

Psychosocial predictors and moderators of weight management programme outcomes in ethnically diverse obese youth

“…The cut‐off for childhood obesity in the USA is ≥95th percentile for gender and age based on the Centers for Disease Control and Prevention growth charts . Paediatric obesity has several negative sequelae including increased risk of diabetes, cardiovascular impairment, musculoskeletal disorders, fatty liver disease and poor quality of life . While family‐based obesity treatment programmes that include a combination of behaviour modification, nutrition education and physical activity have been characterized as the ‘gold standard’ in paediatric obesity treatment, some children do better in these programmes than others .…”