Fast cyclic voltammetry of redox system NAD+/NADH on the copper nanodoped mercury monolayer carbon fiber electrode

Munteanu, Grigore; Dempsey, Eithne; McCormac, Timothy; Munteanu, Corneliu

doi:10.1016/j.jelechem.2011.11.014

Cited by 11 publications

(2 citation statements)

References 22 publications

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“…Metals investigated for the The first example of NADH regeneration involving a metal-catalysed step [1] Top Catal (2014) 57:321-331 323 reduction and oxidation of NAD ? /NADH or analogues (in solution or as electrode materials) include Co [23][24][25], Mn [26], Fe [27], Pd-Au [28], Pt-C [29], Ni-C [29], Cu, Au, Pt-Au [30] Re [31,32], Cu-Hg [33]. Recent reports feature increasingly iridium as the active metal center and address additionally the reverse reaction-the catalytic non-enzymatic oxidation of NAD(P)H under the simultaneous formation of metal hydrides.…”

Section: Pioneering Non-enzymatic Approaches For the Regeneration Of mentioning

confidence: 99%

Recent Trends in Biomimetic NADH Regeneration

2013

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Section: Pioneering Non-enzymatic Approaches For the Regeneration Of mentioning

confidence: 99%

Recent Trends in Biomimetic NADH Regeneration

2013

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“…These methods are starting to make their way into the goal of clinical detection of pyocyanin in patients, some of them also by using commercially available electrodes [ 15 ]. It is common for the studies that detect pyocyanin electrochemically to find that pyocyanin is exclusively detected at negative potentials around −250 mV to −300 mV, claiming that no other chemicals can interfere with this signal [ 16 , 17 ]. Conversely, interferents from dead cells in human fluids can be released and detected at negative potentials, creating misleading results that could falsely be identified as pyocyanin.…”

Section: Introductionmentioning

confidence: 99%

Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry

Alatraktchi

Andersen

Johansen

et al. 2016

Sensors

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Pyocyanin is a virulence factor uniquely produced by the pathogen Pseudomonas aeruginosa. The fast and selective detection of pyocyanin in clinical samples can reveal important information about the presence of this microorganism in patients. Electrochemical sensing of the redox-active pyocyanin is a route to directly quantify pyocyanin in real time and in situ in hospitals and clinics. The selective quantification of pyocyanin is, however, limited by other redox-active compounds existing in human fluids and by other metabolites produced by pathogenic bacteria. Here we present a direct selective method to detect pyocyanin in a complex electroactive environment using commercially available electrodes. It is shown that cyclic voltammetry measurements between −1.0 V to 1.0 V reveal a potential detection window of pyocyanin of 0.58–0.82 V that is unaffected by other redox-active interferents. The linear quantification of pyocyanin has an R2 value of 0.991 across the clinically relevant concentration range of 2–100 µM. The proposed method was tested on human saliva showing a standard deviation of 2.5% ± 1% (n = 5) from the known added pyocyanin concentration to the samples. This inexpensive procedure is suggested for clinical use in monitoring the presence and state of P. aeruginosa infection in patients.

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Low-potential amperometric determination of NADH using a disposable indium-tin-oxide electrode modified with carbon nanotubes

Wang

Bao

et al. 2015

Microchim Acta

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Fast cyclic voltammetry of redox system NAD+/NADH on the copper nanodoped mercury monolayer carbon fiber electrode

Cited by 11 publications

References 22 publications

Recent Trends in Biomimetic NADH Regeneration

Recent Trends in Biomimetic NADH Regeneration

Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry

Low-potential amperometric determination of NADH using a disposable indium-tin-oxide electrode modified with carbon nanotubes

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