Fast and sensitive simultaneous determination of antihypertensive drugs amlodipine besylate and ramipril using an electrochemical method: application to pharmaceuticals and blood serum samples

Abstract

In this work, a simple and sensitive voltammetric method using boron-doped diamond electrode for simultaneous determination of antihypertensive drugs amlodipine besylate and ramipril in pharmaceuticals and biological samples is described.

Hybrid Nanostructure Composed of Homogeneously Decorated MoS2 Nanosheets on Graphene for Simultaneous Electrochemical Determination of Amlodipine and Hydrochlorothiazide

“…28 Two peaks appear at 32°and 57°can be well indexed to (100) and ( 110 I, this value is comparable to the values declared in some previous papers for AML electrochemical oxidation at the surface of different chemically modified electrodes. 18,[41][42][43][44][45] Figure 3 shows the cyclic voltammograms obtained in a 200.0 μM AML solution (voltammogram a with an unmodified SPCE and voltammogram b with the MoS 2 NSs-G/SPCE). The highest oxidation peak potential of AML has been observed at 620 mV for MoS 2 NSs-G/SPCE, which 120 mV more negative in comparison with the signal corresponding to the unmodified SPCE.…”

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“…The literature survey reveals that the determination of Ramipril was done by spectrophotometric methods, [4][5][6][7] HPLC, [8][9][10][11] HPTLC, and electrochemical methods [12][13] . On the other side, Hydrochlorothiazide was determined individually by UV spectroscopy [14][15][16][17] HPLC, 18 HPTLC, [19][20][21] and electrochemical methods.…”

Analytical Applications of Electrochemically Pretreated Boron‐Doped Diamond Electrodes

“…CPT‐BDDEs have also been chosen for the simultaneous determination of different analytes because the surface treatments caused a better separation of the oxidation and/or reduction peak potentials . For instance, Eisele et al .…”