Family interactions in childhood leukemia: an exploratory descriptive study

Moghaddasi, Jaefar; Taleghani, Fariba; Moafi, Alireza; Malekian, Azadeh; Keshvari, Mahrokh; Ilkhani, Mahnaz

doi:10.1007/s00520-018-4289-8

Cited by 20 publications

(21 citation statements)

References 36 publications

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“…In addition to cytogenetic abnormalities, the increased risk of ALL can be associated with different environmental factors. Several case-control studies have introduced heavy smoking, father's freelance job, exposure to low or moderate/high levels of pesticides, and obesity as the most common risk factors associated with the predisposition for ALL in children (Gholami et al, 2011;Moghaddasi et al, 2018;Mohammadi et al, 2018;Urayama et al, 2010). Among all enrolled cases in the current study, 52 (41.6%) were girls and 73 (58.4%) were boys.…”

Section: Discussionmentioning

confidence: 58%

“…Similar to other malignancies, ALL seems to be a multifactorial disease, and environmental and genetic factors interact with each other, playing a key role in its incidence (Eden, 2010). Several studies have demonstrated that environmental and genetic factors such as breastfeeding, keeping children in kindergarten, exposure to radiation, smoking, farm animals, and some inherited diseases (such as Fanconi anemia) can be associated with an increased risk for ALL in children (Gholami et al, 2011;Karimi et al, 2016;Moghaddasi et al, 2018;Mohammadi et al, 2018;Urayama et al, 2010). These findings suggest that knowing risk factors for childhood leukemia, especially ALL, is a crucial step in the prevention and reduction of ALL occurence in childhood.…”

Section: Introductionmentioning

confidence: 99%

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Risk of Acute Lymphoblastic Leukemia: Results of a Case-Control Study

Rafieemehr

Calhor

Esfahani

et al. 2019

Asian Pac J Cancer Prev

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Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Different environmental factors might be effective in the occurrence of this malignancy during childhood. The aim of this study was to find environmental risk factors in childhood ALL in Hamadan, Iran. Methods: This case-control study was done in 2015-2018 on 125 children younger than 15 years of age suffering from ALL. Patients were matched with 130 controls with respect to age, gender, and residence location. The identification of risk factors for ALL was sought based on the comparison of studied variables between case and control individuals. Results: A statistically significant increased risk for ALL was found with regard to type of delivery (OR: 0.

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Section: Discussionmentioning

confidence: 58%

Section: Introductionmentioning

confidence: 99%

Risk of Acute Lymphoblastic Leukemia: Results of a Case-Control Study

Rafieemehr

Calhor

Esfahani

et al. 2019

Asian Pac J Cancer Prev

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“…A review of the literature indicates that chronic and/or terminal illnesses in their children can impact their parents' spousal relationships in a mixture of negative [ 21 , 22 ] and overall positive [ 23 ] manner. Our findings were consistent with this, as some parents expressed increased strength in their marital relationships due to shared experiences of uncertainty and emotional isolation.…”

Section: Discussionmentioning

confidence: 99%

Parental psychosocial aspects and stressors involved in the management of inborn errors of metabolism

Rajasekar

Gannavarapu

Napier

et al. 2020

Molecular Genetics and Metabolism Reports

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Parents of children with inborn errors of metabolism (IEM) face numerous psychosocial challenges. An increased understanding and awareness of these stressors can ensure better overall outcomes for the entire family. We conducted semi-structured, in-person interviews with ten parents to identify psychosocial stressors, strategies, and supports they utilized to overcome their challenges. Our interview guide was designed to elicit familial experiences during the pre- and post-diagnosis periods. The themes and sub-themes were identified through qualitative descriptive textual analysis of audio-recorded transcripts. Major themes identified include ambiguity of illness, changing family and spousal dynamics, and navigating the healthcare system. Sub-themes revolved around disease effects, psychological stressors, health systems, support, and facing the disease. Healthcare professionals have an opportunity to minimize the impact of negative emotional outcomes by assisting families as they navigate the experience of having a child with an IEM. Our findings can be used to develop and continue a more well-rounded, family-oriented framework for IEM management.

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“…Likewise, having more time as a caregiver and spending a greater number of hours taking care of the child were found to influence the caregiver’s proxy-report of QoL. This is because of the fact that, during the disease, affective bonds are created and strengthened over time, helping cope with the disease and to improve the child’s QoL (Moghaddasi et al, 2018; Vlachioti et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

Relationship Between Quality of Life of Children With Cancer and Caregiving Competence of Main Family Caregivers

León

Carreño-Moreno

Arias-Rojas

2020

J Pediatr Oncol Nurs

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Objective: The purpose of this study was to describe the caregiver’s proxy-report of the quality of life (QoL) of children with cancer and the main family caregiver’s competence, and to examine the role of said competence and other care-related variables in their proxy-reported QoL of children with cancer. Method: This was a cross sectional, correlation design study conducted with 97 main family caregivers of children between the ages of 8 and 12 years with cancer residing in Colombia. The following variables were collected: main family caregiver and child sociodemographic characteristics (Survey for Dyad Care; GCPC-UN-D), The Pediatric Quality of Life Inventory 4.0 Cancer Module, and the Competence Instrument (caregiver version). Results: The mean of the children’s QoL was 102.0 points, and the caregivers’ competence score was 211.24. Caregiver’s competence ( t = 5.814, p < .01), marital status ( t = 1.925, p < .05), time as a caregiver ( t = 2.087, p < .05), number of hours spent caring for the child ( t = 2.621, p < .05), and caregiver’s previous caring experiences ( t = 2.068, p < .05) were found to influence caregiver’s proxy-report of the QoL of children with cancer. Conclusions: High competence in main family caregivers positively influence caregiver’s proxy-report of the QoL of children with cancer. Study results also suggest that nurses should consider the caregivers’ sociodemographic characteristics such as marital status, time as a caregiver, number of hours spent caring for the child, and caregiver’s previous experiences because those aspects influence main family caregivers’ proxy-report about their children’s QoL.

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Family interactions in childhood leukemia: an exploratory descriptive study

Cited by 20 publications

References 36 publications

Risk of Acute Lymphoblastic Leukemia: Results of a Case-Control Study

Risk of Acute Lymphoblastic Leukemia: Results of a Case-Control Study

Parental psychosocial aspects and stressors involved in the management of inborn errors of metabolism

Relationship Between Quality of Life of Children With Cancer and Caregiving Competence of Main Family Caregivers

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