2020
DOI: 10.1177/0004563220967569
|View full text |Cite
|
Sign up to set email alerts
|

Faecal immunochemical tests in the COVID-19 pandemic; safety-netting of patients with symptoms and low faecal haemoglobin concentration – can a repeat test be used?

Abstract: Not applicable because this is an editorial

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
10
0

Year Published

2021
2021
2023
2023

Publication Types

Select...
6

Relationship

5
1

Authors

Journals

citations
Cited by 9 publications
(10 citation statements)
references
References 14 publications
(19 reference statements)
0
10
0
Order By: Relevance
“…44 Future research will be required to assess this expanding role of FIT outside the current NICE referral guidelines. With an increasing reliance on FIT as a triage tool for symptomatic patients in primary care, particular attention should be given to the application of repeat FIT (with optimum intervals and thresholds) 45 and the impact of using different cutoff points 33 : safety-netting will become even more vital to avoid missing cancer cases with a negative FIT result. [45][46][47]…”
Section: Discussionmentioning
confidence: 99%
“…44 Future research will be required to assess this expanding role of FIT outside the current NICE referral guidelines. With an increasing reliance on FIT as a triage tool for symptomatic patients in primary care, particular attention should be given to the application of repeat FIT (with optimum intervals and thresholds) 45 and the impact of using different cutoff points 33 : safety-netting will become even more vital to avoid missing cancer cases with a negative FIT result. [45][46][47]…”
Section: Discussionmentioning
confidence: 99%
“…A germane question is whether a repeat FIT after a finding of an increase in f-Hb could help decide whether more traditional surveillance protocols with colonoscopy should be initiated, although there is little available evidence on the possible roles of repeat FIT in any clinical setting. 19 It would also be of interest to investigate if serial f-Hb in patients with NAA and in AA, when f-Hb has fallen, could detect, at an early stage, development of neoplasia; early detection of lesions is another ideal attribute of a tumour marker. Such a strategy is used in IBD to predict recurrence of disease using serial faecal calprotectin measurements (with the patient acting as their own control).…”
Section: Discussionmentioning
confidence: 99%
“…These include the difference between the relative risk and relative odds, the need to estimate the absolute risk reduction that might be gained through this application of f-Hb, the importance of carefully assessing the expected and the accepted false positive rate together with the detection rate, the PPV and its relationship with the prevalence of the disease, and the need for careful assessment of the benefits and risks and burdens such as the impact of this application on the provision of additional health care. Ultimately, after appropriate prospective research, it is possible that the efficacy of these interventions could be monitored by the objective analyses of serial estimates of f-Hb using FIT, although little is known at the present time about the utility of this strategy, particularly in symptomatic patients [44]: the use of serial f-Hb in monitoring responses to interventions in individuals is, as yet, speculative.…”
Section: The Futurementioning
confidence: 99%