2022
DOI: 10.1177/00045632221080897
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Faecal haemoglobin concentration in adenoma, before and after polypectomy, approaches the ideal tumour marker

Abstract: Background Polypectomy may be performed at colonoscopy and then subsequent surveillance undertaken. It is thought that faecal haemoglobin concentration (f-Hb), estimated by quantitative faecal immunochemical tests (FIT), might be a useful tumour marker. Methods Consecutive patients enrolled in colonoscopy surveillance were approached at two hospitals. A specimen for FIT was provided before colonoscopy and, ideally after 3 weeks, a second FIT sample from those who had polypectomy. A single FIT system (OC-Sensor… Show more

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Cited by 3 publications
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“…More restrictive criteria may not only delay diagnosis for some cases of colorectal cancer, but also reduce sensitivity of the pathway for other significant colorectal disease. 9,[41][42][43] Simplifying the clinical categories when compared with the direct access criteria is justified on several grounds. Foremost, the distinction between urgent and non-urgent categories in the direct access criteria appears arbitrary with some non-urgent categories having greater risk of CRC than others afforded urgent investigation.…”
Section: Discussionmentioning
confidence: 99%
“…More restrictive criteria may not only delay diagnosis for some cases of colorectal cancer, but also reduce sensitivity of the pathway for other significant colorectal disease. 9,[41][42][43] Simplifying the clinical categories when compared with the direct access criteria is justified on several grounds. Foremost, the distinction between urgent and non-urgent categories in the direct access criteria appears arbitrary with some non-urgent categories having greater risk of CRC than others afforded urgent investigation.…”
Section: Discussionmentioning
confidence: 99%