Factors predictive of ten-year mortality in severe anorexia nervosa patients

Abstract

Anorexia nervosa in-patients are at high risk of death. This risk can be predicted by both chronicity and seriousness of illness at hospitalization. These elements should be considered as warnings to adapt care provision and could be targeted by treatment.

Re-examining premature mortality in anorexia nervosa: A meta-analysis redux

“…Thus, when comparisons are based on SMRs rather than on disparate mortality rates, elevated mortality in AN may not be out of scale with other psychiatric disorders. Consistent with Arcelus et al [2], and others [70], our analyses revealed higher risk of premature mortality in studies of older participants (based on mean age at entry) and those with relatively few males. However, by extracting additional covariate data, we were able to examine potential confounding.…”

Mortality in eating disorders: A follow-up study of adult eating disorder patients treated in tertiary care, 1995–2010

“…In accordance with previous studies (Fichter et al, 2006;Papadopoulos et al, 2009) mortality in patients with broad AN was elevated at the beginning of the follow-up but decreased over time. Older age at the beginning of treatment in the specialised eating disorder unit elevated the mortality risk in broad AN, which is consistent with findings from earlier studies (Deter et al, 2005;Millar et al, 2005;Huas et al, 2011). About half (45%) of patients with narrow AN and a little over a third (35%) of patients with broad AN had also received inpatient care.…”

“…An important finding of our study was that patients with broad BN have approximately a three-fold risk of premature death which is higher than found in most previous studies (Crow et al, 2009;Arcelus et al, 2011;Huas et al, 2011). Huas et al (2012) found that hospital-treated severe bulimia nervosa patients are at high risk of death (mainly suicide).…”

“…The standardised mortality ratio (SMR) for AN was 5.9 (95% CI: 4.2-8.3) with a mean follow-up period of 14 years (Arcelus et al, 2011). The mortality rates of AN are largely based on cohorts from inpatient settings, while less is known about patients treated in outpatient or community settings (Keel et al, 2003;Huas et al, 2011). Most mortality studies in eating disorders have focused on AN, with few studies on patients with BN and BED (Keel and Brown, 2010;Huas et al, 2012).…”

Self Injurious Behavior in Adolescent Girls with Eating Disorders

“…Contrasting with these reports, Bulik et al (1999) found no difference in the suicide mortality rates among the various types of EDs. Huas et al (2011) identified 6 factors predicting a high mortality risk in severely affected adult AN inpatients: older age, longer duration of ED, history of suicide attempt, misuse of diuretics, intensity of ED symptoms and desired low BMI at admission). Patients with EDs without suicide attempts have a lower suicidal risk.…”