Factors associated with neonatal surgical site infection after abdominal surgery

A meta‐analysis showing the effect of surgical site wound infections and associated risk factors in neonatal surgeries

“…A total of 17 studies reported between 2005 and 2022 satisfied the inclusion criteria for the meta‐analysis among the 1653 distinctive reports. 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 This meta‐analysis study included 18 872 neonates undergoing surgery at the beginning of the study; 1506 were with surgical site wound infections, and 17 366 were without surgical site wound infections as control. All studies evaluated surgical site wound infections' risk factors and effects in neonates undergoing surgery.…”

“…A total of 17 studies reported between 2005 and 2022 satisfied the inclusion criteria for the meta‐analysis among the 1653 distinctive reports 10‐26 . This meta‐analysis study included 18 872 neonates undergoing surgery at the beginning of the study; 1506 were with surgical site wound infections, and 17 366 were without surgical site wound infections as control.…”

“…This meta-analysis comprised 17 studies that included 18 872 neonates undergoing surgery at the beginning of the study; 1506 of them were with surgical site wound infections, and 17 366 were without surgical site wound infections as control. [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] Surgical site wound infections had significantly higher mortality, a longer length of hospital stays, and lower birthweight of neonates compared with no surgical site wound infections for neonates undergoing surgery. However, surgical site wound infections had no notable difference in the gestational age at birth of neonates and the preoperative antibiotic prophylaxis compared with no surgical site wound infections for neonates undergoing surgery.…”

“…This meta‐analysis comprised 17 studies that included 18 872 neonates undergoing surgery at the beginning of the study; 1506 of them were with surgical site wound infections, and 17 366 were without surgical site wound infections as control 10‐26 . Surgical site wound infections had significantly higher mortality, a longer length of hospital stays, and lower birthweight of neonates compared with no surgical site wound infections for neonates undergoing surgery.…”

Update Perioperative Antibiotikaprophylaxe in der Neonatologie

“…Bei Neugeborenen, die aufgrund einer nekrotisierenden Enterokolitis (NEC) operiert werden müssen, ist das Risiko einer SSI deutlich erhöht. Dies ergibt sich aus dem massiv mit Darmbakterien kontaminierten OP Gebiet [3,20]. Solche Patienten erhalten keine PAP, sondern eine kalkulierte Therapie mit Piperacillin-Tazobactam oder Meropenem (mit oder ohne Glykopeptid).…”