Facile green synthesis of non-genotoxic, non-hemolytic organometallic silver nanoparticles using extract of crushed, wasted, and spent Humulus lupulus (hops): Characterization, anti-bacterial, and anti-cancer studies

Das, Pratik; Dutta, Tanusree; Manna, Suvendu; Loganathan, Sravanthi; Basak, Piyali

doi:10.1016/j.envres.2021.111962

Cited by 47 publications

(22 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Recent studies conducted are focused on HA acid coupled with AgNPs to treat and promote faster wound healing, especially in diabetic foot ulcer treatment application. In recent years AgNPs have gained increasing popularity for their medical applications in wound dressings and drug delivery [ 138 ]. Another threat in the field of microorganism management is biofilm.…”

Section: Discussionmentioning

confidence: 99%

Polymeric biomaterials-based tissue engineering for wound healing: a systemic review

et al. 2023

Self Cite

View full text Add to dashboard Cite

Background Biomaterials are vital products used in clinical sectors as alternatives to several biological macromolecules for tissue engineering techniques owing to their numerous beneficial properties, including wound healing. The healing pattern generally depends upon the type of wounds, and restoration of the skin on damaged areas is greatly dependent on the depth and severity of the injury. The rate of wound healing relies on the type of biomaterials being incorporated for the fabrication of skin substitutes and their stability in in vivo conditions. In this review, a systematic literature search was performed on several databases to identify the most frequently used biomaterials for the development of successful wound healing agents against skin damage, along with their mechanisms of action. Method The relevant research articles of the last 5 years were identified, analysed and reviewed in this paper. The meta-analysis was carried out using PRISMA and the search was conducted in major scientific databases. The research of the most recent 5 years, from 2017–2021 was taken into consideration. The collected research papers were inspected thoroughly for further analysis. Recent advances in the utilization of natural and synthetic biomaterials (alone/in combination) to speed up the regeneration rate of injured cells in skin wounds were summarised. Finally, 23 papers were critically reviewed and discussed. Results In total, 2022 scholarly articles were retrieved from databases utilizing the aforementioned input methods. After eliminating duplicates and articles published before 2017, ~520 articles remained that were relevant to the topic at hand (biomaterials for wound healing) and could be evaluated for quality. Following different procedures, 23 publications were selected as best fitting for data extraction. Preferred Reporting Items for Systematic Reviews and Meta-Analyses for this review illustrates the selection criteria, such as exclusion and inclusion parameters. The 23 recent publications pointed to the use of both natural and synthetic polymers in wound healing applications. Information related to wound type and the mechanism of action has also been reviewed carefully. The selected publication showed that composites of natural and synthetic polymers were used extensively for both surgical and burn wounds. Extensive research revealed the effects of polymer-based biomaterials in wound healing and their recent advancement. Conclusions The effects of biomaterials in wound healing are critically examined in this review. Different biomaterials have been tried to speed up the healing process, however, their success varies with the severity of the wound. However, some of the biomaterials raise questions when applied on a wide scale because of their scarcity, high transportation costs and processing challenges. Therefore, even if a biomaterial has good wound healing qualities, it may be technically unsuitable for use in actual medical scenarios. All of these restrictions have been examined closely in this review.

show abstract

Section: Discussionmentioning

confidence: 99%

Polymeric biomaterials-based tissue engineering for wound healing: a systemic review

et al. 2023

Self Cite

View full text Add to dashboard Cite

show abstract

“…Adapted from Refs. [ 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 ].…”

Section: Figureunclassified

Bell Shape Curves of Hemolysis Induced by Silver Nanoparticles: Review and Experimental Assay

et al. 2022

View full text Add to dashboard Cite

The hemolytic activity assay is a versatile tool for fast primary toxicity studies. This work presents a systematic study of the hemolytic properties of ArgovitTM silver nanoparticles (AgNPs) extensively studied for biomedical applications. The results revealed an unusual and unexpected bell-shaped hemolysis curve for human healthy and diabetic donor erythrocytes. With the decrease of pH from 7.4 and 6.8 to 5.6, the hemolysis profiles for AgNPs and AgNO3 changed dramatically. For AgNPs, the bell shape changed to a step shape with a subsequent sharp increase, and for AgNO3 it changed to a gradual increase. Explanations of these changes based on the aggregation of AgNPs due to the increase of proton concentration were suggested. Hemolysis of diabetic donor erythrocytes was slightly higher than that of healthy donor erythrocytes. The meta-analysis revealed that for only one AgNPs formulation (out of 48), a bell-shaped hemolysis profile was reported, but not discussed. This scarcity of data was explained by the dominant goal of studies consisting in achieving clinically significant hemolysis of 5–10%. Considering that hemolysis profiles may be bell-shaped, it is recommended to avoid extrapolations and to perform measurements in a wide concentration interval in hemolysis assays.

show abstract

“…Valorization of jackfruit peel for the production of SCNCs which have many applications in food, paper, optics, pharma, environmental remediation, composite synthesis, etc. Similarly, non-genotoxic, non-hemolytic organometallic silver nanoparticles using spent hop extracts were synthesized in greenway, characterized, and showed antibacterial and anti-cancer properties having potential application in the medical industry (Das et al 2022) As with developing nations, India can adopt certain measures for food waste management, such as partnering with charity organizations and food banks to ensure the distribution of excess food from retail outlets to those in need. Food that has passed its expiration date and cannot be donated can be composted or transformed into biofuel for retail commercial vehicles.…”

Section: Contemporary Trends In Food Waste Disposal In Indiamentioning

confidence: 99%

Insights into the management of food waste in developing countries: with special reference to India

Sahoo

Dwivedi

Madheshiya

et al. 2022

Preprint

View full text Add to dashboard Cite

Up to one-third of the food that is purposely grown for human sustenance is wasted and never consumed, with adverse consequences for the environment and socio-economic aspects. In India, managing food waste is a significant environmental concern. Food waste output is increasing in Indian cities and towns as a result of the country's urban expansion, modernization, and population growth. Poor management of food waste can have negative consequences for the environment and pose a risk to the public's health issues. This review focuses on the current challenges, management strategies, and future perspectives of food waste management in India. The efficient management of food waste involves a comprehensive study regarding the characterization of food waste and improved waste management methods. In addition, the government policies and rules for managing food waste that is in effect in India are covered in this review.

show abstract

Facile green synthesis of non-genotoxic, non-hemolytic organometallic silver nanoparticles using extract of crushed, wasted, and spent Humulus lupulus (hops): Characterization, anti-bacterial, and anti-cancer studies

Cited by 47 publications

References 74 publications

Polymeric biomaterials-based tissue engineering for wound healing: a systemic review

Polymeric biomaterials-based tissue engineering for wound healing: a systemic review

Bell Shape Curves of Hemolysis Induced by Silver Nanoparticles: Review and Experimental Assay

Insights into the management of food waste in developing countries: with special reference to India

Contact Info

Product

Resources

About