Facile and green synthesis of phytochemicals capped platinum nanoparticles and in vitro their superior antibacterial activity

Tahir, Kamran; Nazir, Sadia; Ahmad, Aftab; Li, Baoshan; Khan, Arif Ullah; Khan, Zia Ul Haq; Khan, Faheem Ullah; Khan, Qudrat Ullah; Khan, Abrar; Rаhmаn, Аziz Ur

doi:10.1016/j.jphotobiol.2016.12.016

Cited by 141 publications

(50 citation statements)

References 38 publications

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“…Thus, Cr 2 O 3 NPs have shown significant biological applications. Smaller size NPs with larger surface area have shown numerous applications in the field of medicine, chemo, and electrochemistry (Khan et al, ; Tahir et al, ).…”

Section: Resultsmentioning

confidence: 99%

Facile green synthesis approach for the production of chromium oxide nanoparticles and their different in vitro biological activities

Iqbal

Abbasi

Munir

et al. 2020

Microscopy Res & Technique

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Green synthesis of nanoparticles using plants has become a promising substitute for the conventional chemical synthesis methods. In the present study, our aim was to synthesize chromium oxide nanoparticles (Cr 2 O 3 NPs) through a facile, low-cost, ecofriendly route using leaf extract of Rhamnus virgata (RV). The formation of Cr 2 O 3 NPs was confirmed and characterized by spectroscopic profile of UV-Vis, EDX, FTIR, and XRD analyses. The UV-visible spectroscopy has confirmed the formation of Cr 2 O 3 NPs by the change of color owing to surface plasmon resonance. The bioactive functional groups present in the leaf extract of RV involved in reduction and stabilization of Cr 2 O 3 NPs were determined by FTIR analysis. Based on XRD analysis, crystalline nature of Cr 2 O 3 NPs was determined. The morphological shape and elemental composition of Cr 2 O 3 NPs were investigated using SEM and EDX analyses, respectively. With growing applications of Cr 2 O 3 NPs in biological perspectives, Cr 2 O 3 NPs were evaluated for diverse biopotentials. Cr 2 O 3 NPs were further investigated for its cytotoxicity potentials against HepG2 and HUH-7 cancer cell lines (IC 50 : 39.66 and 45.87 μg/ml), respectively. Cytotoxicity potential of Cr 2 O 3 NPs was confirmed against promastigotes (IC 50 : 33.24 μg/ml) and amastigotes (IC 50 : 44.31 μg/ml) using Leishmania tropica (KMH 23 ). The Cr 2 O 3 NPs were further evaluated for antioxidants, biostatic, alpha-amylase, and protein kinase inhibition properties. Biocompatibility assay was investigated against human macrophages which confirmed the nontoxic nature of Cr 2 O 3 NPs. Overall, the synthesized Cr 2 O 3 NPs are biocompatible and nontoxic and proved to possess significant biopotentials. In future, different in vivo studies are needed to fully investigate the cytotoxicity and mechanism of action associated with these Cr 2 O 3 NPs. K E Y W O R D S anticancer, antileishmanial, antimicrobial, biocompatibility, Cr 2 O 3 NPs, protein kinase

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Section: Resultsmentioning

confidence: 99%

Facile green synthesis approach for the production of chromium oxide nanoparticles and their different in vitro biological activities

Iqbal

Abbasi

Munir

et al. 2020

Microscopy Res & Technique

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“…TEM image in ( Figure 4D) shows that ZnONPs are hexagonal in shape with average size of~18 nm which are consistent with calculation from XRD. Smaller size NPs with larger surface area have shown numerous applications especially in the field of medicine, chemo, and electrochemistry [46,47]. EDX spectra analysis revealed the surface chemical composition of biogenic ZnONPs.…”

Section: Biosynthesis Of Znonpsmentioning

confidence: 99%

“…DLS is performed to confirm the size of NPs in colloid suspension in the range of nano and submicron, and its ZP measurement is based on particles movement under electric field. surface area have shown numerous applications especially in the field of medicine, chemo, and electrochemistry [46,47]. EDX spectra analysis revealed the surface chemical composition of biogenic ZnONPs.…”

Section: Biosynthesis Of Znonpsmentioning

confidence: 99%

Bioactivities of Geranium wallichianum Leaf Extracts Conjugated with Zinc Oxide Nanoparticles

et al. 2019

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This study attempts to obtain and test the bioactivities of leaf extracts from a medicinal plant, Geranium wallichianum (GW), when conjugated with zinc oxide nanoparticles (ZnONPs). The integrity of leaf extract-conjugated ZnONPs (GW-ZnONPs) was confirmed using various techniques, including Ultraviolet–visible spectroscopy, X-Ray Diffraction, Fourier Transform Infrared Spectroscopy, energy-dispersive spectra (EDS), scanning electron microscopy, transmission electron microscopy, and Raman spectroscopy. The size of ZnONPs was approximately 18 nm, which was determined by TEM analysis. Additionally, the energy-dispersive spectra (EDS) revealed that NPs have zinc in its pure form. Bioactivities of GW-ZnONPs including antimicrobial potentials, cytotoxicity, antioxidative capacities, inhibition potentials against α-amylase, and protein kinases, as well as biocompatibility were intensively tested and confirmed. Altogether, the results revealed that GW-ZnONPs are non-toxic, biocompatible, and have considerable potential in biological applications.

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“…Among the metallic nanomaterials, silver nanoparticles are of the greatest interest due to their particular physical and chemical properties and biocidal activity against wide range of microorganisms [29][30][31]. Other noble metal nanoparticles including gold and platinum nanoparticles have proved some antimicrobial activity [32][33][34][35][36].…”

Section: Antimicrobial Activity Studymentioning

confidence: 99%

Effectiveness of Biosynthesized Trimetallic Au/Pt/Ag Nanoparticles on Planktonic and Biofilm Enterococcus faecalis and Enterococcus faecium Forms

Długaszewska

Dobrucka

2019

J Clust Sci

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A simple, effective and environmentally friendly green synthesis was demonstrated to obtain trimetallic Au/Pt/Ag nanoparticles using Lamii albi flos extract. The formed nanoparticles (NPs) were characterized by Ultraviolet-Visible, Fourier-Transform Infrared, Scanning Electron Microscopy, Transmission Electron Microscopy, and Atomic Force Microscopy measurements. The applied physicochemical methods indicated that the size of synthesized Au/Pt/Ag NPs was in the range of 35-40 nm. The antimicrobial activity of the obtained nanoparticles was assessed using Gram-positive, Gram-negative bacteria and yeasts, including standard strains of Staphylococcus aureus NCTC 4163, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922 and Candida albicans ATCC 10231. Also, antibacterial and antibiofilm activities of novel nanoparticles were studied using clinical strains of Enterococcus spp. The obtained Au/Pt/Ag NPs revealed excellent antimicrobial effects against planktonic and sessile clinical strains of Enterococcus faecalis and Enterococcus faecium.

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Facile and green synthesis of phytochemicals capped platinum nanoparticles and in vitro their superior antibacterial activity

Cited by 141 publications

References 38 publications

Facile green synthesis approach for the production of chromium oxide nanoparticles and their different in vitro biological activities

Facile green synthesis approach for the production of chromium oxide nanoparticles and their different in vitro biological activities

Bioactivities of Geranium wallichianum Leaf Extracts Conjugated with Zinc Oxide Nanoparticles

Effectiveness of Biosynthesized Trimetallic Au/Pt/Ag Nanoparticles on Planktonic and Biofilm Enterococcus faecalis and Enterococcus faecium Forms

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