Fabrication of silk fibroin/poly(lactic-co-glycolic acid)/graphene oxide microfiber mat via electrospinning for protective fabric

Liu, Zulan; Shang, Songmin; Chiu, Ka-lok; Dai, Fangyin

doi:10.1016/j.msec.2019.110308

Cited by 27 publications

(11 citation statements)

References 60 publications

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“…With the unique molecular structure and excellent biocompatibility, SF is conducive to cell adhesion and growth. 18,19 SF can promote wound healing by increasing the cell growth, proliferation, and migration of different cells types involved in the different phases of the wound healing process. 20,21 It is widely used for tissue engineering, drug release and some other biomedical materials.…”

Section: Introductionmentioning

confidence: 99%

“…Silk fibroin (SF), riched in 18 kinds of amino acids, is a high molecular protein extracted from natural silk. With the unique molecular structure and excellent biocompatibility, SF is conducive to cell adhesion and growth 18,19 . SF can promote wound healing by increasing the cell growth, proliferation, and migration of different cells types involved in the different phases of the wound healing process 20,21 .…”

Section: Introductionmentioning

confidence: 99%

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Silk fibroin/polycaprolactone nanofibrous membranes loaded with natural Manuka honey for potential wound healing

Lan

Zhang

et al. 2021

J of Applied Polymer Sci

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Antibacterial wound dressing, an effective barrier between the wound and the foreign environment, has the ability to inhibit and even kill the bacteria around the wound so that it can accelerate the wound healing. However, the loaded antibacterial agents of antibiotics and metal ions on wound dressings caused the new problems of drug resistance and toxicity. To develop a novel wound dressing with the natural antibacterial property agent, here, natural Manuka honey (MH), silk fibroin (SF), and polycaprolactone (PCL) were mixed to prepare nanofibrous membranes by electrospinning. The SEM observation showed the good microscopic morphology of SF/PCL/MH nanofibrous membranes that the fibers were even and smooth. With the addition of MH, the membranes gained the accepted stress and the excellent flexibility to adapt to wound contour. In addition, their hydrophilic property was beneficial to cell adhesion and proliferation. Most importantly, SF/PCL/MH nanofibrous membranes exhibited excellent sustained release effect and antibacterial properties.The antibacterial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans reached 99.88%, 99.70%, and 98.95%, respectively when 75% natural antimicrobial agent MH was loaded. Moreover, SF/PCL/MH membranes showed good cytocompatibility. These results indicated the fabricated SF/PCL/MH nanofibrous membranes are a kind of novel dressing with good antimicrobial property.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Silk fibroin/polycaprolactone nanofibrous membranes loaded with natural Manuka honey for potential wound healing

Lan

Zhang

et al. 2021

J of Applied Polymer Sci

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“…Chemical formula Solvent Reference Collagen HFIP [42] Gelatin TFE/acetic acid [43,44] Silk fibroin HFIP [45,46] Elastin HFIP [47] ultrasonication, and magnetic field assistance are vital to the success of electrospinning. For colloidal particles, electrospinning can also be smoothly realized, due to the colloidal particles maintaining adequate interactions as a result of entanglement with the jets.…”

Section: Methodsmentioning

confidence: 99%

Two Sides of Electrospun Fiber in Promoting and Inhibiting Biomedical Processes

Wang

Cui

2020

Advanced Therapeutics

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Electrospinning is a versatile technique for generating ultrathin fibers, which is widely applied in various biomedical applications. The properties and structures of the fibers are specifically engineered to meet the needs of particular applications. The impact of nanofibrous scaffolds on biological processes is related to the promotion or inhibition of specific cell or bioactive substance functions. Here, a novel analysis of the diverse roles of electrospun nanofibrous scaffolds is provided and recent advances in exploiting their binary attributes for applications in biomedicine are summarized. This review initially introduces the development techniques for electrospinning, specifically the engineering of electrospun nanofibers. Then, scaffold applications for cell migration, adhesion, proliferation, and accelerating regeneration in cardiac, nerve, skeletal muscle, bone tissue, and wound healing are presented. Moreover, their inhibitory properties in cancer treatments, antibacterial applications, anti‐adhesion, anti‐scarring, and inhibition of thrombus formation are summarized. Eventually, the potential for future work using multifunctional, electrospun, nanofibrous scaffolds, in order to further inspire the development of scaffolds for biomedical treatments is summarized and discussed.

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“…Electrospun nanobers are widely used not only in tissue engineering, wound dressings, drug delivery systems, enzyme immobilization and biosensors, but also in protective textiles, cosmetics, facial masks and antibacterial materials. 92,115,146,147 Sinha et al 148 described the characteristics and specic applications of electrospun nanobers as biomedical textiles, with special emphasis on its application in strategic defense. The nonwovens prepared have sufficient bending resistance and wear resistance.…”

Section: Other Aspectsmentioning

confidence: 99%

Application of blocking and immobilization of electrospun fiber in the biomedical field

Ning

Shen

2020

RSC Adv.

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Fabrication of silk fibroin/poly(lactic-co-glycolic acid)/graphene oxide microfiber mat via electrospinning for protective fabric

Cited by 27 publications

References 60 publications

Silk fibroin/polycaprolactone nanofibrous membranes loaded with natural Manuka honey for potential wound healing

Silk fibroin/polycaprolactone nanofibrous membranes loaded with natural Manuka honey for potential wound healing

Two Sides of Electrospun Fiber in Promoting and Inhibiting Biomedical Processes

Application of blocking and immobilization of electrospun fiber in the biomedical field

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