Fabrication of a template-synthesized gold nanorod-modified electrode for the detection of dopamine in the presence of ascorbic acid

Simultaneous Electrochemical Detection of Dopamine, Ascorbic Acid and Uric Acid Using Copper-Phthalocyanine Functionalized MWCNTS

“…This requires understanding the complexity of the brain and its interconnectivity. In detection of neurotransmitter DA is electrochemical active on some electrode surfaces, via its oxidation, so the design of active electrodes for dopamine detection has received a great interest in electroanalysis [7][8][9] . Unfortunately, ascorbic acid (AA) and uric acid (UA) are always coexisting with DA in living organisms, sharing a similar oxidation potential so they interfere with the electrochemical detection of DA.…”

New self-assembled layers composed with gold nanoparticles, cysteamine and dihydrolipoic acid deposited on bare gold template for highly sensitive and selective simultaneous sensing of dopamine in the presence of interfering ascorbic and uric acids

“…When using the prepared, in this work, gold electrode modified with SAM layers composed with dihydrolipoic acid, cysteamine and the gold nanoparticles, the peak potential separations between dopamine and ascorbic acid (ΔE DA-AA = 0.39 V), between dopamine and uric acid (ΔE DA-UA = 0.50 V) and between ascorbic acid and uric acid (ΔE AA-UA = 0.89 V) are much greater at the prepared modified gold electrode in comparison with those at the unmodified gold electrode (ΔE DA-AA = 0.03 V), (ΔE DA-UA = 0.06 V) and (ΔE AA-UA = 0.028 V). Since the gold nanoparticles used in the present paper are stabilized by citrate and thus target the negative charge [68,69], it seems reasonable to conclude that their chemisorption on the top of the prepared SAM layers leads to a SAM matrix with an excess of negative charge. Thus, the electrode surface covered by the prepared SAM film should repel anionic species through electrostatic repulsion while cationic species should be attracted.…”

Porous Para-aminobenzoic Acid Membrane Prepared by Electrochemical Method and Its Application in Voltammetric Determination of Dopamine

“…Thus, great attention has been paid to the development of functional electrode systems for detection of DA. It is well known that the selective detection of DA in biological media requires differentiation from the signal interference due to ascorbic acid (AA), which exhibits an oxidation potential close to that of DA and results in voltammetric response overlap [7]. In addition, a considerably higher concentration of AA than DA in real samples makes selective detection of DA even more difficult.…”