New self-assembled layers composed with gold nanoparticles, cysteamine and dihydrolipoic acid deposited on bare gold template for highly sensitive and selective simultaneous sensing of dopamine in the presence of interfering ascorbic and uric acids

Abstract

A gold bare template modified with self-assembled layers (SAMs) composed of gold nanoparticles and organic Scontaining compound: cysteamine and dihydrolipoic acid were prepared. The electrode with SAMs endowed with gold nanoparticles gave a high catalytic effect for dopamine electrooxidation alone and in the presence of biogenic interfering compounds: ascorbic acid and uric acid in solution at pH 7. For this novel sensor, a linear relationship between the current response of dopamine at the potential of peak maximum (j p ) and the concentration of this compound in solution (c DA ) was found over the range 0.1 μM to 0.85 mM with the detection limit of 0.023 μM.

Peroxidase-like Fe3O4 Nanoparticle/Few-Layered Graphene Composite for Electrochemical Detection of Dopamine, Ascorbic Acid, and Uric Acid

“…It is evident from the available literature that regardless of the type of conductive material utilized as the active sensing material in an electrochemical sensor, the presence of both AA and UA along with DA will not have any effect on the simultaneous quantitative detection of each other. Examples of such materials include bimetallic Pd–Ag nanoflowers/rGO or Pt–Ni/rGO, gold templates modified with organic sulfides, gold nanoparticles etc. − Additionally, in the case of DPV based simultaneous quantitative detection of interfering molecules, the oxidation peaks/potentials will not overlap due to electrostatic interactions because the p K a (the acid dissociation constant) values of the respective molecules have distinct disparity (For example: p K a = 4.1, 5.4, 8.87, 9.22, and 9.53 for AA, UA, DA, etilefrine hydrochloride, and acetaminophen, respectively). However, it is important to be careful in quantitative electrochemical detection of interfering molecules while simultaneously changing their concentrations. , …”

Prussian Blue Analogue-Derived Iron Sulfide–Cobalt Sulfide Nanoparticle-Decorated Hollow Nitrogen-Doped Carbon Nanocubes for the Selective Electrochemical Detection of Dopamine

“…The hydrogen bonds between the amine groups or the hydroxyl groups in DA and the nitrogen heteroatoms in the N-doped carbon matrix are conducive to selective adsorption and catalysis of DA . Therefore, CoS 2 –FeS 2 /HNCC can act similar to “electron antennae” competently tunneling electrons between the solute and the electrode, which can improve the sensing performance for DA …”

“…51 Therefore, CoS 2 −FeS 2 /HNCC can act similar to "electron antennae" competently tunneling electrons between the solute and the electrode, which can improve the sensing performance for DA. 52 Selectivity, Reusability, Reproducibility, and Stability. To evaluate the selectivity of this sensor, we also determined DPV curves of 50 μM DA and 250 μM of different interfering substances.…”

A nanogold supported inorganic/organic hybrid 3D sensor for electrochemical quantification of propranolol—effective antagonist of β-adrenergic receptors

“…According to literature, the presence of both AA and UA in the mixture with DA has no effect on the simultaneous quantitative detection of these compounds when measurements are carried out on modified electrodes, regardless of the type of conductive material used in the electrochemical sensor. For example, such results were observed on different carbon, or noble metal electrodes modified with organic sulfur compounds and gold nanoparticles or on reduced graphene oxide modified with bimetallic alloyed nanoparticles [64][65][66][67][68]. In this study, the effect of possible interference of uric acid, ascorbic acid, and dopamine on propranolol determination was examined.…”