Fabrication and optimisation of a fused filament 3D-printed microfluidic platform

Tothill, Alexander M.; Partridge, Matthew; James, Stephen W.; Tatam, Ralph P.

doi:10.1088/1361-6439/aa5ae3

Cited by 60 publications

(38 citation statements)

References 22 publications

(37 reference statements)

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“…Fused Filament Fabrication technology can be successfully implemented to produce functional lab on-a chip devices, while appropriate process parameter fine-tuning can resolve a number of the issues that are inherently present in lab-on-a-chip manufacturing through this 3D printing approach. Tothill et al [37] designed and manufactured a microfluidic device using a commercial FFF 3D printer, using PLA and PET filaments. The authors highlight the drawbacks that common FFF filament materials present in terms of limited transparency which is a commonly needed feature in LOC devices.…”

Section: Lab-on-a-chipmentioning

confidence: 99%

“…Increasing print speed was not found to influence transparency in a consistent manner, slightly increasing or decreasing transparency depending on the layer height of the print setup. The authors demonstrate that suitable process optimization led to the development of a functional device for performing optical colorimetric assays [37].…”

Section: Lab-on-a-chipmentioning

confidence: 99%

“…Selection of high-resolution printers for accurate microchannel construction is preferable. As layer height has been demonstrated to be one of the most influential factors for manufacturing efficient LOC devices [37,38], minimum layer height capabilities should be assessed, in accordance with the dimensional requirements for the printed devices.…”

Section: Equipment Selectionmentioning

confidence: 99%

See 2 more Smart Citations

3D-Printed Lab-on-a-Chip Diagnostic Systems-Developing a Safe-by-Design Manufacturing Approach

Karayannis¹,

Petrakli²,

Gkika³

et al. 2019

Micromachines

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The aim of this study is to provide a detailed strategy for Safe-by-Design (SbD) 3D-printed lab-on-a-chip (LOC) device manufacturing, using Fused Filament Fabrication (FFF) technology. First, the applicability of FFF in lab-on-a-chip device development is briefly discussed. Subsequently, a methodology to categorize, identify and implement SbD measures for FFF is suggested. Furthermore, the most crucial health risks involved in FFF processes are examined, placing the focus on the examination of ultrafine particle (UFP) and Volatile Organic Compound (VOC) emission hazards. Thus, a SbD scheme for lab-on-a-chip manufacturing is provided, while also taking into account process optimization for obtaining satisfactory printed LOC quality. This work can serve as a guideline for the effective application of FFF technology for lab-on-a-chip manufacturing through the safest applicable way, towards a continuous effort to support sustainable development of lab-on-a-chip devices through cost-effective means.

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Section: Lab-on-a-chipmentioning

confidence: 99%

Section: Lab-on-a-chipmentioning

confidence: 99%

Section: Equipment Selectionmentioning

confidence: 99%

See 1 more Smart Citation

3D-Printed Lab-on-a-Chip Diagnostic Systems-Developing a Safe-by-Design Manufacturing Approach

Karayannis¹,

Petrakli²,

Gkika³

et al. 2019

Micromachines

View full text Add to dashboard Cite

show abstract

“…Fused Filament Fabrication technology can be successfully implemented to produce functional lab on-a chip devices, while appropriate process parameter fine-tuning can resolve a number of the issues that are inherently present in lab-on-a-chip manufacturing through this 3D printing approach. Tothill [37] et al designed and manufactured a microfluidic device using a commercial FFF 3D printer, using PLA and PET filaments. The authors highlight the drawbacks that common FFF filament materials present in terms of limited transparency which is a commonly needed feature in LOC devices.…”

Section: Lab-on-a-chipmentioning

confidence: 99%

“…Additionally, small layer heights (e.g. 60 μm [37]) have been observed to produce structures of increased transparency, so it is reasonable to suggest this setting to print microfluidic devices. Through this approach, increased mechanical stability may also be achieved [124].…”

Section: Shell Number and Layer Heightmentioning

confidence: 99%

3D Printed Lab-on-a-Chip Diagnostic Systems - Developing a Safe-by-Design Manufacturing Approach

Karayannis¹,

Petrakli²,

Gkika³

et al. 2019

Preprint

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The aim of this study is to provide a detailed strategy for Safe-by-Design (SbD) 3D printed lab-on-a-chip (LOC) device manufacturing, using Fused Filament Fabrication (FFF) technology. At first, the applicability of FFF in lab-on-a-chip device development is briefly discussed. Subsequently, a methodology to categorize, identify and implement SbD measures for FFF is suggested. Furthermore, the most crucial health risks involved in FFF processes are examined, placing the focus on the examination of ultrafine particle (UFP) and Volatile Organic Compound (VOC) emission hazards. Thus, a SbD scheme for lab-on-a-chip manufacturing is provided, while also taking into account process optimization for obtaining satisfactory printed LOC quality. This work can serve as a guideline for the effective application of FFF technology for lab-on-a-chip manufacturing through the safest applicable way, towards a continuous effort to support sustainable development of lab-on-a-chip devices through cost-effective means.

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Tuning the Solar Performance of Building Facades through Polymer 3D Printing: Toward Bespoke Thermo‐Optical Properties

Piccioni

Leschok

Grobe

et al. 2023

Adv Materials Technologies

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sector accounts for 34% of energy demand and 37% of energy-related CO 2 emissions globally. [2] In buildings, a major portion of the footprint concentrates in the first year of the life cycle and results from embodied emission of material and components. This relative contribution is expected to reach values as high as 50% of the total emissions as energy efficiency in buildings increases. [3] At the moment, despite the continued power sector decarbonization and the adoption of climate-change mitigation policies, buildings remain offtrack to achieve carbon neutrality by 2050. [1] Facades constitute the main building boundary between external and internal environments, controlling the flow of energy and matter inside buildings. For this reason, they considerably impact the environmental conditions of indoor spaces, user satisfaction, and operational efficiency. [4] Therefore, improvements in the performance of building facades are critical to meet most of Net Zero Emissions by 2050 scenario reductions in energy use. [5] To meet the performance requirements prescribed by the building codes, advanced facades systems have been proposed, which can tune their behavior in response to variable boundary conditions [6][7][8] and feature smart materials allowing integration of and switching between multiple functionalities. [9][10][11] Apart from the operational Façades are the primary interface controlling the flow of solar energy in buildings and affecting their energy balance and environmental impact. Recently, large-scale 3D printing (3DP) of translucent polymers has been explored as a technique for fabricating façade components with bespoke properties and functionalities. Transmissivity is essential for building facades, as the response to solar radiation is crucial to obtaining comfort and greatly affects electricity and cooling demands. However, it is still unclear how 3DP parameters affect the optical properties of translucent polymers. This study establishes an experimental procedure to relate the optical properties of PETG components to design and 3DP parameters. It is observed that printing parameters control layer deposition, which governs internal light scattering in the layers and overall light transmission. Moreover, the layer resolution determines angle-dependent properties. It is shown that printing parameters can be tuned to obtain tailored optical properties, from high normal transparency (≈90%) to translucency (≈60%), and with a range of haze levels (≈55-97%). These findings present an opportunity for large-scale 3DP of bespoke façades, which can selectively admit or block solar radiation and provide uniform daylighting of a space. In the context of the building sector decarbonization, such components hold great potential for reducing emissions while ensuring occupant comfort.

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Fabrication and optimisation of a fused filament 3D-printed microfluidic platform

Cited by 60 publications

References 22 publications

3D-Printed Lab-on-a-Chip Diagnostic Systems-Developing a Safe-by-Design Manufacturing Approach

3D-Printed Lab-on-a-Chip Diagnostic Systems-Developing a Safe-by-Design Manufacturing Approach

3D Printed Lab-on-a-Chip Diagnostic Systems - Developing a Safe-by-Design Manufacturing Approach

Tuning the Solar Performance of Building Facades through Polymer 3D Printing: Toward Bespoke Thermo‐Optical Properties

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