Fabrication and characterization of luminescent Pr3+ doped fluorapatite nanocrystals as bioimaging contrast agents

Milojkov, Dušan V.; Silvestre, Óscar F.; Stanić, Vojislav; Janjić, Goran V.; Mutavdžić, Dragosav; Milanović, Marija; Nieder, Jana B.

doi:10.1016/j.jlumin.2019.116757

Cited by 24 publications

(16 citation statements)

References 50 publications

(74 reference statements)

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“…63 The UC fluorescence is caused by the transition of Er 3+ when receiving the energy from Yb 3+ . The observation of an NIR fluorescence (950–1100 nm) was resulted from the 2 F 5/2 → 2 F 7/2 transition of Yb 3+ in the DC process under the excitation of 380 nm.…”

Section: Properties and Luminescence Principlesmentioning

confidence: 99%

“…And the inset is the TEM image of sample (a). The emission spectra of Gd 2 (WO 4 ) 3 : Yb 3+ /Ho 3+ and Gd 2 (WO 4 ) 3 : Yb 3+ /Ho 3+ @SiO 2 UCNPs under 980 nm irradiation (500 μg/mL, 0.5 W/cm – 2 ). Inset is the digital photo of sample upon 980 nm irradiation (b).…”

Section: Improvement Of Fluorescence Intensitymentioning

confidence: 99%

“…Bioimaging is becoming more and more important in cancer diagnosis, intraoperative guidance, and postoperative evaluation. [1][2][3][4][5] It interacts with biological tissues or organs by light, ultrasound, X-ray, and electromagnetic fields, and then the feedback is transmitted to the detector, which is then fed into the computer, thus generating the morphology and structure information about biological tissues, organs, and tumor. New imaging technologies, such as magnetic resonance imaging (MRI), computed tomography (CT), photon avalanche (PA), positron emission tomography (PET), and singlephoton emission computed tomography (SPECT), are now available in the clinic, and these models, combined with a variety of cleverly designed imaging contrast agents, can be used for disease diagnosis and therapy monitoring.…”

Section: Introductionmentioning

confidence: 99%

“…19 However, the main limitation is their low quantum yield. (2) Quantum dots (QDs): they possess the advantages including high stability, high quantum yield, and brightly fluorescent emission. A variety of NIRemission QDs has been widely applied for the bioimaging, such as Ag 2 S, 20 Ag 2 Se, 21 CdS, 22 and PbS.…”

Section: Introductionmentioning

confidence: 99%

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Application of rare earth-doped nanoparticles in biological imaging and tumor treatment

et al. 2020

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Rare earth-doped nanoparticles have been widely used in disease diagnosis, drug delivery, tumor therapy, and bioimaging. Among various bioimaging methods, the fluorescence imaging technology based on the rare earth-doped nanoparticles can visually display the cell activity and lesion evolution in living animals, which is a powerful tool in biological technology and has being widely applied in medical and biological fields. Especially in the band of near infrared (700–1700 nm), the emissions show the characteristics of deep penetration due to low absorption, low photon scattering, and low autofluorescence interference. Furthermore, the rare earth-doped nanoparticles can be endowed with the water solubility, biocompatibility, drug-loading ability, and the targeting ability for different tumors by surface functionalization. This confirms its potential in the cancer diagnosis and treatment. In this review, we summarized the recent progress in the application of rare earth-doped nanoparticles in the field of bioimaging and tumor treatment. The luminescent mechanism, properties, and structure design were also discussed.

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Section: Properties and Luminescence Principlesmentioning

confidence: 99%

Section: Improvement Of Fluorescence Intensitymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Application of rare earth-doped nanoparticles in biological imaging and tumor treatment

et al. 2020

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“…Further, the emission depends on the dopant concentration as well. The praseodymium-doped fluorapatite illustrated green emission at 545 nm and orange emission at 600 nm [52]. Europium/barium co-doped and F-substituted nHAp (HA@nFAp:Eu/Ba) showed high sensitivity in both computed tomography and fluorescence imaging [53].…”

Section: Introductionmentioning

confidence: 99%

Impact of Dopants on the Electrical and Optical Properties of Hydroxyapatite

Arul¹,

Ramya²,

Kalkura³

2020

Biomaterials

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This chapter deals with the effect of alternating electrical current on hydroxyapatite [HAp, Ca10(PO4)6(OH)2] and doped HAp along with their optical response and the processes involved. The dielectric constant, permittivity and ac conductivity were analyzed to have an insight into the surface charge polarization phenomenon. Further, the magnitude and the polarity of the surface charges, microstructure, and phases also play significant role in the cell proliferation and growth on the implants. Besides, the mechanism behind the electrical properties and the healing of bone fracture are discussed. The influence of various dopants on the optical properties of HAp viz., absorbance, transmission, band gaps and defects energy levels are analyzed along with the photoluminescence and excitation independent emission. In the future outlook, the analysis of effect of doping is summarized and its impact on the next generation biomaterials are elucidated.

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Cascade luminescence and antibacterial behavior of fluorapatite nanopowder co-doped with Pr3+, NO3− and CO32− ions

et al. 2022

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Fabrication and characterization of luminescent Pr3+ doped fluorapatite nanocrystals as bioimaging contrast agents

Cited by 24 publications

References 50 publications

Application of rare earth-doped nanoparticles in biological imaging and tumor treatment

Application of rare earth-doped nanoparticles in biological imaging and tumor treatment

Impact of Dopants on the Electrical and Optical Properties of Hydroxyapatite

Cascade luminescence and antibacterial behavior of fluorapatite nanopowder co-doped with Pr3+, NO3− and CO32− ions

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