Extramedullary Solitary Plasmacytoma: Demonstrating the Role of 18F-FDG PET Imaging

Gautam, Archana; Sahu, Kamal Kant; Alamgir, Ahsan; Siddiqi, Imran; Ailawadhi, Sikander

doi:10.7860/jcdr/2017/22801.9557

Cited by 12 publications

(15 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[14] We have also recently reported EMPs in duodenum, pancreas, and ovary in a single patient. [2] Similar to our case, Vailati et al . have also reported plasmacytoma of the thyroid as an initial presentation of MM.…”

supporting

confidence: 89%

See 1 more Smart Citation

Thyroid plasmacytoma: A rare cause of hoarseness of voice

et al. 2019

View full text Add to dashboard Cite

supporting

confidence: 89%

“…With the aid of the present case and our previously reported cases of plasmacytomas involving rare sites such as frontal bone, duodenum, pancreatic head, and ovary, we aim to enrich the knowledge of our readers about the unusual presentations and rare locations of extramedullary plasmacytomas (EMPs). [23]…”

mentioning

confidence: 99%

Thyroid plasmacytoma: A rare cause of hoarseness of voice

et al. 2019

View full text Add to dashboard Cite

“…On 18 FDG PET/CT images, the maxSUV difference in 18 FDG uptake can distinguish between benign and malignant lesions in many cases. [1,2,7,8,17] MRI is also a good tool to differentiate primary or metastatic malignant spine tumors from benign compression fractures. However, occasionally, this distinction is difficult.…”

Section: Discussionmentioning

confidence: 99%

PET/CT-negative malignant spine tumor with pathologic fracture

2018

View full text Add to dashboard Cite

Rationale:We report on a patient with a positron emission tomography/computed tomography scans (PET/CT)-negative malignant spine tumor, which had even caused a pathologic fracture, and was eventually confirmed on surgical biopsy.Patient concerns:A 67-year-old man visited our emergency department with sudden onset of lower extremities paraplegia after slip down. On examination, gradually increasing paralysis was observed in both lower limbs.Diagnoses:Plain radiograph and CT showed an acute burst fracture at T12 with an osteolytic mass lesion within the vertebral body and pedicle, causing severe encroachment of the spinal canal. Magnetic resonance imaging (MRI) revealed a bulging posterior cortex of the T12 vertebral body, which suspected a pathologic fracture due to malignancy. However, PET/CT showed a benign burst fracture, which was confirmed by a senior radiologist.Intervention:We planned surgery for emergent decompression of the spinal cord, temporary stabilization, and tissue biopsy. The histologic evaluation confirmed the lesion to be a malignant solitary bone plasmacytoma (SBP). Seven days later, definite surgery in the form of pedicle screw fixation and posterolateral bone graft from T8 to L2 was performed. Four weeks after the definite surgery, the patient underwent radiation therapy for 2 months.Outcomes:Three weeks postoperatively, lower extremity motor function fully recovered, and ambulation with support was possible. One year postoperatively, spine MRI showed no evidence of local recurrence, and complete decompression of the spinal cord was achieved.Lessons:Spine surgeons should bear in mind that malignant spine tumors could be misinterpreted as benign on PET/CT.

show abstract

“…Therefore, MRI is advised as a routine staging procedure during the workup of EMP 11. 18FDG-PET/CT examines the whole body in a faster and single study, with a sensitivity of 96% and a specificity of 77% 12. In fact, PET/CT is mandatory for confirming a diagnosis of EMP according to the updated 2017 International Myeloma Working Group guidelines 13.…”

Section: Discussionmentioning

confidence: 99%

<p>Multiple extramedullary plasmacytomas of the trachea and pharyngeal tissue: a case report and literature review</p>

Tang¹,

Wang²,

Liang³

et al. 2019

OTT

View full text Add to dashboard Cite

Extramedullary plasmacytoma (EMP) is an infrequent form of plasma cell dyscrasia that presents as a mass of monoclonal plasma cells located in extramedullary soft tissues with no skeletal component. EMP constitutes ~4% of all plasma cell neoplasms and occurs mostly in the upper respiratory tract. Here, we report a rare case of multiple EMPs involving the trachea, laryngopharynx, and oropharynx, which caused symptoms of airway obstruction as the only clinical manifestation. The patient was diagnosed by histopathology of the tissue from bronchoscopic resection and successfully managed with bronchoscopic intervention to treat lesions in the trachea and radiotherapy combined with surgical resection to treat lesions in the pharynx. There was no recurrence after 14 months of follow-up. Endoscopic intervention plays a key role in the rapid diagnosis and treatment of EMP involving the central airways.

show abstract

Extramedullary Solitary Plasmacytoma: Demonstrating the Role of 18F-FDG PET Imaging

Cited by 12 publications

References 12 publications

Thyroid plasmacytoma: A rare cause of hoarseness of voice

Thyroid plasmacytoma: A rare cause of hoarseness of voice

PET/CT-negative malignant spine tumor with pathologic fracture

<p>Multiple extramedullary plasmacytomas of the trachea and pharyngeal tissue: a case report and literature review</p>

Contact Info

Product

Resources

About