Extraction of phenolic compounds from pepper-rosmarin (Lippia sidoides Cham.) leaves by sequential extraction in fixed bed extractor using supercritical CO2, ethanol and water as solvents

Trends for the Application of Passion Fruit Industrial By-products: A Review on the Chemical Composition and Extraction Techniques of Phytochemicals

“…[61] extracted, in sequential steps, bioactive substances from cherries using CO 2 and ethanol and concluded that the sequential process produces extracts more concentrated and with higher biological activity. Similar conclusions were obtained by Garmus et al [62] and [63] for sequential extraction of pitanga and pepper-rosmarin leaves.…”

Supercritical CO2 extraction of bioactive compounds from radish leaves: Yield, antioxidant capacity and cytotoxicity

“…The amount of functional compounds recovered from raw plant materials depends on the used method for extraction [1]. The conventional techniques to obtain plant extracts, such as hydrodistillation and solvent extraction, have a number of disadvantages that are related with the use of high amounts of organic solvents and consequently the production of toxic solvent waste [2,3].…”

“…The use of supercritical carbon dioxide (scCO2) has been accepted in the last decades, because is chemically inert, non-polar, non-toxic, and non-flammable as well as an accepted food grade solvent. Also, scCO2 has shown an optimal behavior as extraction solvent for thermolabile compounds [1,4]. Thus, Supercritical Fluid Extraction (SFE) by using CO2 can be employed as an alternative to conventional methods for extracting and/or fractionating functional compounds [3,4].…”

Prospection of Enzyme Modulators in Aqueous and Ethanolic Extracts of Lippia sidoides Leaves: Genotoxicity, Digestion, Inflammation, and Hemostasis

“…[4] Thus, it was included in the list of the Brazilian National List of Medicinal Plants of Interest to the Unified Health System (RENISUS) as one of the plants with the potential to generate phytotherapeutic medicines for use in public health. [5] The essential oil of L. sidoides has great commercial and pharmacological value, due to its main constituents, thymol and carvacrol, and its antiseptic, antimicrobial, antioxidant, and anti-inflammatory properties. [4] Hydroalcoholic extracts have already been used for the treatment of cutaneous wounds as an oral antiseptic and in liquid soap preparations to prevent and treat fungal infections in the body.…”