Extraction of phenolic compounds from rosemary using choline chloride – based Deep Eutectic Solvents

Wojeicchowski, José Pedro; Marques, Caroline; Igarashi‐Mafra, Luciana; Coutinho, J.; Mafra, Marcos R.

doi:10.1016/j.seppur.2020.117975

Cited by 97 publications

(57 citation statements)

References 52 publications

(64 reference statements)

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“…In Table 6 are shown various types of bioactive compounds along with their sources, which are extracted using DESs, as mentioned [137][138][139][140][141][142][143][144][145][146][147][148][149][150][151][152].…”

Section: Extraction Of Biomoleculesmentioning

confidence: 99%

Revisiting the Physicochemical Properties and Applications of Deep Eutectic Solvents

2022

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Recently, deep eutectic solvent (DES) or ionic liquid (IL) analogues have been considered as the newest green solvent, demonstrating the potential to replace harsh volatile organic solvents. DESs are mainly a combination of two compounds: hydrogen bond acceptor (HBA) and hydrogen bond donor (HBD), which have the ability to interact through extensive hydrogen bonds. A thorough understanding of their physicochemical properties is essential, given their successful applications on an industrial scale. The appropriate blend of HBA to HBD can easily fine-tune DES properties for desired applications. In this context, we have reviewed the basic information related to DESs, the two most studied physicochemical properties (density and viscosity), and their performance as a solvent in (i) drug delivery and (ii) extraction of biomolecules. A broader approach of various factors affecting their performance has been considered, giving a detailed picture of the current status of DESs in research and development.

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Section: Extraction Of Biomoleculesmentioning

confidence: 99%

Revisiting the Physicochemical Properties and Applications of Deep Eutectic Solvents

2022

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“…Wojeicchowski et al [ 60 ] screened ten DESs to extract phenolic compounds from rosemary ( Rosmarinus officinalis L.) leaves. The extraction was done by heating and stirring at 30 °C and 600 rpm for 15 min with a liquid-solid ratio of 20:1.…”

Section: Phenolic Compound Extraction From Natural Sourcesmentioning

confidence: 99%

Latest Insights on Novel Deep Eutectic Solvents (DES) for Sustainable Extraction of Phenolic Compounds from Natural Sources

et al. 2021

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Phenolic compounds have long been of great importance in the pharmaceutical, food, and cosmetic industries. Unfortunately, conventional extraction procedures have a high cost and are time consuming, and the solvents used can represent a safety risk for operators, consumers, and the environment. Deep eutectic solvents (DESs) are green alternatives for extraction processes, given their low or non-toxicity, biodegradability, and reusability. This review discusses the latest research (in the last two years) employing DESs for phenolic extraction, solvent components, extraction yields, extraction method characteristics, and reviewing the phenolic sources (natural products, by-products, wastes, etc.). This work also analyzes and discusses the most relevant DES-based studies for phenolic extraction from natural sources, their extraction strategies using DESs, their molecular mechanisms, and potential applications.

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“…The extraction of total polyphenols from rosemary leaves using choline chloride and 1,2-propaneidol at 65 °C in a liquid-to-solid ratio of 40:1 resulted in a 78-mg gallic acid equivalent with an antioxidant activity of 80-mg equivalents of Trolox [ 96 ], where the proportion of total polyphenols extracted was approximately 220% higher compared to the control in which 70% ethanol was used.…”

Section: Application Of Environmentally Friendly Techniques In Sommentioning

confidence: 99%

Environmentally Friendly Techniques and Their Comparison in the Extraction of Natural Antioxidants from Green Tea, Rosemary, Clove, and Oregano

Calderón‐Oliver

Ponce‐Alquicira

2021

Molecules

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Many current food and health trends demand the use of more ecological, sustainable, and environmentally friendly techniques for the extraction of bioactive compounds, including antioxidants. However, extraction yields and final antioxidant activities vary between sources and are highly influenced by the given extraction method and nature and ratio of the employed solvent, especially for total polyphenols, flavonoids, and anthocyanins, which are well recognized as natural antioxidants with food applications. This review focused on the most common extraction techniques and potential antioxidant activity in the food industry for various natural antioxidant sources, such as green tea, rosemary, clove, and oregano. Green extraction techniques have been proven to be far more efficient, environmentally friendly, and economical. In general, these techniques include the use of microwaves, ultrasound, high hydrostatic pressure, pulsed electric fields, enzymes, and deep eutectic solvents, among others. These extraction methods are described here, including their advantages, disadvantages, and applications.

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Extraction of phenolic compounds from rosemary using choline chloride – based Deep Eutectic Solvents

Cited by 97 publications

References 52 publications

Revisiting the Physicochemical Properties and Applications of Deep Eutectic Solvents

Revisiting the Physicochemical Properties and Applications of Deep Eutectic Solvents

Latest Insights on Novel Deep Eutectic Solvents (DES) for Sustainable Extraction of Phenolic Compounds from Natural Sources

Environmentally Friendly Techniques and Their Comparison in the Extraction of Natural Antioxidants from Green Tea, Rosemary, Clove, and Oregano

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