Extraction, identification and quantitative HPLC analysis of flavonoids from sarang semut (Myrmecodia pendan)

Engida, Adam Mekonnen; Kasim, Novy S.; Tsigie, Yeshitila Asteraye; Ismadji, Suryadi; Huynh, Lien Huong; Ju, Yi‐Hsu

doi:10.1016/j.indcrop.2012.04.043

Cited by 93 publications

(71 citation statements)

References 28 publications

(29 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Flavonoids are polyphenol compounds derived from 2-phenylchromane commonly found in many plants, vegetables and flowers [24]. Flavonoids have several benefits for human health, such as antioxidant activity, anti-proliferative, anti-cancer, anti-bacterial, anti-inflammatory, anti-allergic and anti-viral effects [24].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The N-Hexane Fraction of Myrmecodia Pendans Inhibits Cell Survival and Proliferation in Colon Cancer Cell Line

Bashari¹,

Hidayat²,

Ruswandi³

et al. 2018

Int J Pharm Pharm Sci

View full text Add to dashboard Cite

Objective: Despite advanced treatment options available for colorectal cancer, many reported resistance and unresponsiveness to conventional chemotherapeutic agents. Therefore, it is urgent to discover a novel drug for colon cancer. Sarang Semut (Myrmecodia pendans), an Indonesian native plant, has been studied extensively due to its anti-cancer profiles. This study aimed to evaluate the anti-tumour activity of Sarang Semut in colon cancer cells. Methods:We evaluated cytotoxic activity of methanol extract as well as n-hexane and ethyl acetate fraction towards colon cancer cell lines (Caco-2 and HCT-116 cells) utilizing 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay. The most potent fraction was evaluated further in inhibiting cell survival using MTT assay and cell proliferation using trypan blue exclusion assay as well as a clonogenic assay. Results:Our data showed that the n-hexane fraction of Sarang Semut induces more cell death than the methanol extract and ethyl acetate fraction. Therefore, we analyzed the n-hexane fraction further and found that the inhibitory concentration 50% (IC50 Conclusion:The n-hexane fraction of Sarang Semut demonstrates a high potential antitumor activity in colon cancer cell line.) of the n-hexane fraction was 24 and 30 parts per million (ppm) for Caco-2 and HCT-116 cells, respectively. Moreover, it inhibited cell growth as well as cell colony formation, in particular, shown by the plating efficiency (P<0.05) and colony area per seed (P<0.01) of the control group were different to the treatment group.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Flavonoids have several benefits for human health, such as antioxidant activity, anti-proliferative, anti-cancer, anti-bacterial, anti-inflammatory, anti-allergic and anti-viral effects [24].…”

Section: Discussionmentioning

confidence: 99%

The N-Hexane Fraction of Myrmecodia Pendans Inhibits Cell Survival and Proliferation in Colon Cancer Cell Line

Bashari¹,

Hidayat²,

Ruswandi³

et al. 2018

Int J Pharm Pharm Sci

View full text Add to dashboard Cite

show abstract

“…Ant nest administration tends to increase the feed efficiency to increase body weight. It is suspected that ant nest (Myrmecodia pendans) contains flavonoids active substances [21].…”

Section: Feed Convertion Ratiomentioning

confidence: 99%

The Effect of Treatment Ant Nest (Myrmecodia pendans) on Quail Production and Performance (Coturnix-coturnix japonica)

Gaol

Sudjarwo

Djunaidi

2016

JELS

View full text Add to dashboard Cite

This research was aimed to determine the effect of ant nest treatment (Myrmecodia pendans) on quail production and performance. Research sample was 250 quails. Ant nest was administered in 5 treatments and 5 replications: P 0 (0%) as control treatment, P 1 (0.2%), P 2 (0.4%), P 3 (0.6%), and P 4 (0.8 %) treatments. Data were collected from quails at 28 days to 70 days old. Variables measured were the performance and quail's egg production. This study was designed using completely randomized design. Real significant difference were examined utilizing Duncan's Multiple Range Test (DMRT). Analysis of variance result showed that ant nest provide significant influence to feed intake and Hen Day Production (P <0.05). The highest average of feed consumption is treatment P 4 (0.8%), whereas treatment P 0 (0%) was the lowest average for feed consumption. Feed conversion rate in treatment P 4 (0.8%) was more efficient compared to other treatments. Ant nests administering did not result significantly different (P> 0.05) to feed conversion and egg mass. The results of the study concluded that higher ant nest administration is capable of increasing quails feed intake and Hen Day Production.

show abstract

“…In previous studies, sarang semut shown to contain flavanoids after tested using HPLC. Whereas using gas chromatography testing, sarang emut proven to contain alcohol group, alkaloid group, and free compound such as N and O [4].…”

Section: Introductionmentioning

confidence: 99%

Eco-friendly green inhibitor of mild steel in 3,5% NaCl solution by Sarang Semut (Myrmecodia Pendans) extract

Pradityana¹,

Sulistijono²,

Shahab³

et al. 2014

AIP Conference Proceedings

View full text Add to dashboard Cite

Extraction, identification and quantitative HPLC analysis of flavonoids from sarang semut (Myrmecodia pendan)

Cited by 93 publications

References 28 publications

The N-Hexane Fraction of Myrmecodia Pendans Inhibits Cell Survival and Proliferation in Colon Cancer Cell Line

The N-Hexane Fraction of Myrmecodia Pendans Inhibits Cell Survival and Proliferation in Colon Cancer Cell Line

The Effect of Treatment Ant Nest (Myrmecodia pendans) on Quail Production and Performance (Coturnix-coturnix japonica)

Eco-friendly green inhibitor of mild steel in 3,5% NaCl solution by Sarang Semut (Myrmecodia Pendans) extract

Contact Info

Product

Resources

About