2006
DOI: 10.2214/ajr.05.0370
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Extraadrenal Paragangliomas of the Body: Imaging Features

Abstract: Although paragangliomas can occur in a variety of anatomic locations, the majority are seen in relatively predictable regions of the body. Extraadrenal paragangliomas have nearly identical imaging features, including a homogeneous or heterogeneous hyperenhancing soft-tissue mass at CT, multiple areas of signal void interspersed with hyperintense foci (salt-and-pepper appearance) within tumor mass at MRI, and an intense tumor blush with enlarged feeding arteries at angiography.

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Cited by 203 publications
(215 citation statements)
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“…Paragangliomas are observed in patients of all ages; however, they have been found to occur more frequently during the 2nd decade of life and the ratio of female to male patients is 3:2 (11-13). The most common site for paragangliomas is the organ of Zuckerkandl at the distal aorta or aortic bifurcation and less commonly, they are observed in the head, neck, thorax and bladder (14). The first case of a paraganglioma of the bladder was described by Zimmerman et al (15) in 1953.…”
Section: Discussionmentioning
confidence: 99%
“…Paragangliomas are observed in patients of all ages; however, they have been found to occur more frequently during the 2nd decade of life and the ratio of female to male patients is 3:2 (11-13). The most common site for paragangliomas is the organ of Zuckerkandl at the distal aorta or aortic bifurcation and less commonly, they are observed in the head, neck, thorax and bladder (14). The first case of a paraganglioma of the bladder was described by Zimmerman et al (15) in 1953.…”
Section: Discussionmentioning
confidence: 99%
“…PG cases with metastatic disease may be administered chemotherapeutic agents including cyclophosphamide, vincristine, and dacarbazine. Symptoms of local compression can be treated with radiotherapy for palliation (Lee et al, 2006). Since our patient was considered inoperable as a result of pericardial invasion, she already lost chance for surgical cure.…”
Section: Discussionmentioning
confidence: 96%
“…Also called glomus tumor, chemodectoma, carotid body tumor, or receptoma, these tumors are rare and slowly growing neuroendocrine tumors (Sobol and Dailey, 1990). They are most commonly located at the bifurcation of common carotid artery, jugular foramen, aortic arch, and retroperitoneum (Lee et al, 2006). Tumors arising from adrenal medulla are called pheochromocytoma.…”
Section: Introductionmentioning
confidence: 99%
“…Paragangliomas are rare neuroendocrine tumors originating from the autonomic ganglia, with pathological features indistinguishable from pheochromocytomas (72,73). Generally, these lesions are associated with hormone secretion (catecholamines), with a high rate of malignant behavior (up to 25%) (74,75).…”
Section: Discussionmentioning
confidence: 99%