2015
DOI: 10.3892/ol.2015.3222
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Non-functioning paraganglioma occurring in the urinary bladder: A case report and review of the literature

Abstract: Abstract. Paraganglioma, also termed extra-adrenal pheochromocytoma, may be observed at the base of the skull and neck as well as within the mediastinum and periaortic region. The clinical symptoms of paraganglioma of the urinary bladder include intermittent hypertensive attacks, micturition, headaches and palpitations due to high catecholamine levels; these types of paragangliomas are extremely rare. However, certain bladder paragangliomas do not present with any of these symptoms; thus, surgeons are not pre-… Show more

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Cited by 13 publications
(10 citation statements)
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References 21 publications
(18 reference statements)
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“…In the genitourinary tract, renal pelvis (4.9%) is the third primary site of paragangliomas, following behind the bladder (79.2%) and urethra (12.7%) (2). It has been reported that 97% of paragangliomas were considered benign and occurred more frequently in women between 30 and 40 years of age (3).…”
Section: Discussionmentioning
confidence: 99%
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“…In the genitourinary tract, renal pelvis (4.9%) is the third primary site of paragangliomas, following behind the bladder (79.2%) and urethra (12.7%) (2). It has been reported that 97% of paragangliomas were considered benign and occurred more frequently in women between 30 and 40 years of age (3).…”
Section: Discussionmentioning
confidence: 99%
“…Notably, α-receptor antagonist should be administered to stabilize hypertension before operation and avoid hypertensive crisis occurring throughout the surgical procedure when patients are suspected to have functional paragangliomas (2).…”
Section: Discussionmentioning
confidence: 99%
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“…In the bladder, it can produce symptoms typical of pheochromocytoma, including hematuria and micturition syncope resulting from the release of catecholamines by bladder contraction. In 10-15% of cases, paragangliomas of the bladder are nonfunctioning; another 10% show hormonal activity without clinical expression ( 4 ) .…”
mentioning
confidence: 99%