External versus Endoscopic Dacryocystorhinostomy for Acquired Nasolacrimal Duct Obstruction in a Tertiary Referral Center

Simon, Guy J. Ben; Joseph, Jeffrey M.; Lee, Seongmu; Schwarcz, Robert; McCann, John D.; Goldberg, Robert A.

doi:10.1016/j.ophtha.2005.03.015

Cited by 261 publications

(211 citation statements)

References 36 publications

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“…The success rate for EES-DCR, however, varies markedly from 54 to 96%. [1][2][3][4][5][6][7][8] Numerous modifications have been developed to promote ostial patency, ranging from various methods of producing the nasal mucosal and/or lacrimal sac flaps, 2,4,[9][10][11][12] varying the size of the bony ostium, 4,[12][13][14] lacrimal sac incision, 15 to stenting. 16,17 Nevertheless, ostial closure or obstruction still occurs, mostly due to excessive scars/synechia or granulation formation at the ostium.…”

Section: Introductionmentioning

confidence: 99%

“…16,17 Nevertheless, ostial closure or obstruction still occurs, mostly due to excessive scars/synechia or granulation formation at the ostium. 3,5,6,8,9,[18][19][20] Some authors advocate the use of mitomycin C (MMC) intraoperatively to reduce fibrosis formation, [21][22][23][24][25][26] although granulation tissue has been reported to form around the ostia following MMC application during EES-DCR. 27,28 Hyaluronan is a ubiquitous polysaccharide component of the extracellular matrix.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Merogel coverage on wound healing and ostial patency in endonasal endoscopic dacryocystorhinostomy for primary chronic dacryocystitis

Cannon

Yan

et al. 2011

Eye

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Purpose To investigate the effects of Merogel coverage on ostial patency in endonasal endoscopic dacryocystorhinostomy (EES-DCR) for primary chronic dacryocystitis (PCD). Methods In all, 260 patients with unilateral PCD were randomized into two groups: the Merogel group and the control group. All patients underwent EES-DCR. The Merogel group received Merogel covering the wound 1-2 mm around the ostium and the control group received no treatment. Patients were followed up for 9 months. The mucosal epithelialization of the wound, the proliferation of fibrosis tissue, and the success rate of ostial patency were compared. Results Our study included 112 patients in the Merogel group and 115 patients in the control group. At the 2-week review, intact mucosal epithelium lined the ostia in 96 Merogel patients compared with 80 control patients (ITT analysis: v 2 ¼ 4.502, P ¼ 0.034). At the 9-month review, scars were present in 18 patients in the Merogel group compared with 39 patients in the control group (ITT analysis: v 2 ¼ 9.909, P ¼ 0.002, ITT analysis). No differences were observed in the granulation formation between the two groups. The success rate of ostial patency reached 94.6% (106/112) in the Merogel group compared with 80% (92/115) in the control group (ITT analysis: v 2 ¼ 4.151, P ¼ 0.042). Conclusion Merogel coverage may enhance the success rate of EES-DCR for PCD by promoting mucosal epithelial healing and preventing excessive scarring.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of Merogel coverage on wound healing and ostial patency in endonasal endoscopic dacryocystorhinostomy for primary chronic dacryocystitis

Cannon

Yan

et al. 2011

Eye

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“…8 We therefore use relief of symptoms as the measure of success for surgery. Many different techniques of DCR have been described in literature.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the results endonasal dacrocystorhinostomy in patients with DCR

Vaghela

Patel

et al. 2017

Int J Otorhinolaryngol Head Neck Surg

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Background: Dacrocystitis refers to a series of clinical entities characterized by inflammation of lacrimal sac which leads to obstruction at the level of drainage of lacrimal system. Owing to the initial encouraging results and simplicity of the operation, it is decided that all symptomatic patients with lacrimal drainage obstruction would be treated initially by endoscopic endonasal dacrocystorhinostomy method, irrespective of the level of obstruction. Methods: A total 50 patients were included in the study over a period of 3-4 months. They were subjected to endonasal dacrocystorhinostomy and were evaluated for postoperative complications. Results: Very few complications were seen postoperatively suggesting that this newer technique may be useful. Conclusions: Endonasal dacrocystorhinostomy may prove better in coming years.

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“…In some studies, the authors advocated that external DCR procedures had higher success rates when compared with the endonasal method, and some other authors had asserted that both methods had the same success rates or endonasal method is superior to external method. [9][10][11] Different opinions about success rates stated for DCR procedures in the literature stem from scarce number of prospective, randomized and controlled comparative studies between external and endoscopic DCR procedures.…”

Section: Discussionmentioning

confidence: 99%