2008
DOI: 10.1590/s1984-29612008000200007 View full text |Buy / Rent full text
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Abstract: Cellular detoxification and excretion enzymes are important to the maintenance of cellular homeostasis. In this work mRNA transcription, protein expression and enzymatic activity of Glutathione S-transferases (GSTs), enzymes involved in the excretion of endo and xenobiotic compounds were analyzed. These parameters are elements believed to protect cells against chemical toxicity and oxidative stress in different tissues (salivary gland, ovary and synganglion) from partially engorged females and engorged females… Show more

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“…We observed an association of these factors with the increased GST activity. In ticks, endogenous oxidative damage was generated by the products of the metabolism obtained from food intake, and associated with increased GST activity (Freitas et al 2008). We also observed that the depth of the temporary ponds was an important factor influencing the levels of TBARS and GST activity.…”
Section: Discussionmentioning
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“…We observed an association of these factors with the increased GST activity. In ticks, endogenous oxidative damage was generated by the products of the metabolism obtained from food intake, and associated with increased GST activity (Freitas et al 2008). We also observed that the depth of the temporary ponds was an important factor influencing the levels of TBARS and GST activity.…”
Section: Discussionmentioning
“…We suggest that GST may have an important function during the period of sexual maturation and pre-posture, acting possibly in the process of biotransformation of sexual hormones secreted in this stage. Freitas et al (2008) and Pinheiro and Oliveira (2016) also suggest GST at this stage of the animals' life cycle; however, with ticks and crayfish, respectively. GSTs are present in different organisms and are important for the intracellular biotransformation of endo and xenobiotics (Papadopoulos et al 2004).…”
Section: Discussionmentioning
“…In humans there is an increase in infectious diseases such as conjunctivitis [ 60 ]. Glutathione S transferase Acts as an antioxidant in the eye system [ 61 , 62 ]. Polymeric immunoglobulin receptor This glycoprotein has already been described in tear samples of humans.…”
Section: Discussionmentioning
“…Glutathione S-transferases (GSTs) denotes a superfamily of catalytic proteins that are present in almost all living beings, being distributed in a great diversity of aerobic organisms, ranging from bacteria to human [10][11]. These enzymes are involved in several biological processes [13].…”
Section: Highlightsmentioning