Experimental study of the tissue reaction caused by the presence of cellulose produced

Abstract

The cellulose blanket produced by Acetobacter xylinum presented good biocompatibility, remained stable during the entire study period, and could be considered a good material for elevating the nasal dorsum.

Antimicrobial Brazilian Propolis (EPP-AF) Containing Biocellulose Membranes as Promising Biomaterial for Skin Wound Healing

“…In addition, in vivo studies have demonstrated that BC membranes are biocompatible and can be used as scaffold for tissue engineering [39–41]. …”

The Efficacy of Electron Beam Irradiated Bacterial Cellulose Membranes as Compared with Collagen Membranes on Guided Bone Regeneration in Peri-Implant Bone Defects

“…Some in vivo studies have reported that BC membranes implanted in the subcutaneous tissue of rats were not resorbed after 12 weeks, and induced mild inflammatory response until 30 days after transplantation with no signs of foreign bodies around implanted membranes [ 32 , 33 ]. In another study, BC membranes implanted in the dura mater of dogs partially disappeared at 270 days post-transplantation [ 34 ], and BC grafted in the nasal dorsum of rabbits exhibited slight fragmentation at six months without foreign body reaction [ 35 ]. Although non-degradable BC is an effective scaffold for long term support, its lack of biodegradability limits its use as a resorbable barrier membrane [ 36 ].…”

Bacterial Cellulose as Laryngeal Medialization Material: An Experimental Study

“…It has also been used as a substitute for meninges, dorsum of the nose, tympanic membrane, as a lining for intravascular prostheses, and in the trachea to avoid circumferential stenosis. [25][26][27][28] Although the material has been tested in other animal models, the evaluation did not included the larynx; hence, situations, such as tissue reaction, material absorption, and extrusion, need to be addressed to evaluate its usefulness as a material for laryngeal reconstruction. The aim of this study was to evaluate the medialization, inflammatory response, and healing of rabbit vocal folds after implantation of a membrane of bacterial cellulose.…”