Experimental Mycotoxicosis in Layer Induced by Ochratoxin A and its Amelioration with Herbomineral Toxin Binder ‘Toxiroak’

Sawale, G. K.; Gosh, R. C.; Ravikanth, K.; Maini, S.; Rekhe, D. S.

doi:10.3923/ijps.2009.798.803

Cited by 33 publications

(37 citation statements)

References 25 publications

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“…During the same study, a diet contaminated with 1 mg OTA/kg caused a reduction in feed consumption over the entire period, and a lower body weight of the OTA‐treated broiler chickens compared with the non‐treated ones. Similar results were presented by other authors (Prior et al., ; Manning and Wyatt, ; Huff et al., ; Hoehler et al., ; Raju and Devegowda, ; Stoev et al., ,; Garcia et al., ; Santin et al., ; Verma et al., ; Sawale et al., ). Huff et al.…”

Section: Discussionsupporting

confidence: 88%

Feeding a diet contaminated with ochratoxin A for chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 1. Effects on growth and slaughter performance, haematological and serum traits

Pozzo

Salamano

Mellia

et al. 2013

Animal Physiology Nutrition

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SummaryThe European Commission Recommendation 2006/576/EC, suggests that the maximum level of Ochratoxin A (OTA) in poultry feeds should be set at 0.1 mg OTA/kg. Thirty-six one-day-old male Hubburd broiler chickens were divided into two groups, a Control (basal diet) and an Ochratoxin A (basal diet + 0.1 mg OTA/kg) group. The growth and slaughter performance traits were recorded. The liver, spleen, bursa of Fabricius and thymus weights were measured. The erythrocyte and leukocyte numbers were assayed in blood samples, and the heterophils to lymphocytes (H/L) ratio was determined. Alpha-1-acid glycoprotein (AGP), lysozyme, the total protein and the electrophoretic pattern were evaluated in serum samples. Liver enzymes (alanino aminotransferase, ALT and aspartate aminotransferase, AST) and kidney function parameters (uric acid and creatinine) were quantified. The results revealed that feeding a 0.1 mg OTA/kg contaminated diet to chicks caused a decrease in the absolute thymus weight (p < 0.05) and a lower total protein (p < 0.01), albumin (p < 0.01), alpha (p < 0.05), beta (p = 0.001) and gamma (p = 0.001) globulins serum concentration in the Ochratoxin A group. Moreover, the albumin-to-globulin (A/G) ratio of the OTA-treated animals resulted to be higher (p < 0.05). Feeding broiler chickens, a diet contaminated with the maximum level admitted by the European Commission Recommendation (0.1 mg OTA/kg), did not affect the animal performance, slaughter traits, organ weights, haematological parameters, liver enzyme or renal function parameters concentrations but had an overall immunosuppressant effect, with reduction in the thymus weight and of the total serum protein, albumin, alpha, beta and gamma globulins concentration.

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Section: Discussionsupporting

confidence: 88%

Feeding a diet contaminated with ochratoxin A for chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 1. Effects on growth and slaughter performance, haematological and serum traits

Pozzo

Salamano

Mellia

et al. 2013

Animal Physiology Nutrition

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“…Kurkure et al (2001) reported that Turmeric restored the reduced humoral response caused by aflatoxin induced immuno-suppression, suggesting humoral immunestimulatory potential. Sawale et al (2009) recorded increased haemagglutination titre in laying hens treated with herbomineral toxin binder containing C. longa. Serum antibody titre was significantly higher in Turmeric fed broilers challenged with EtMIC2, an apical complex protein which plays an important role in host cell invasion of Eimeria parasites (Lee et al, 2010).…”

Section: Anti-coccidial Effectsmentioning

confidence: 97%

“…Radwan et al (2008) reported that egg production, weight and mass increased significantly in laying hens fed Turmeric at the level of 0.5% in the basal diet, while yolk weight and yolk index were significantly higher in the group fed with 1.0% Turmeric in the feed. Sawale et al (2009) recorded increased egg production in laying hens treated with a herb-derived mineral toxin binder production containing Curcuma longa. Radwan et al (2008) suggested that Curcuma longa may improve the environment in the uterus (specifically the site of calcium deposition) and consequently increase shell weight and thickness.…”

Section: Introductionmentioning

confidence: 96%

The use of Turmeric (Curcuma longa) in poultry feed

Khan

Naz

Javdani

et al. 2012

World's Poultry Science Journal

104

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There is growing interest in developing natural alternatives to antibiotic growth promoters in order to maintain both birds' performance and health. In the last decade, Turmeric has been extensively used in poultry diets. Turmeric is a natural herb of the ginger family, Zingiberaceae. Wide range medicinal properties of this plant have been advocated. In poultry feed, Turmeric has been extensively used in different concentrations, dosages and durations. In this review, the beneficial effects of this plant on growth, weight gain, feed conversion ratio, ameliorative effect on liver health, immunomodulatory and antioxidative effects are reviewed

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“…In an experiment, feeding OTA at 2 mg/Kg diet to broiler chicks for 42 days, Santin et al (2002) reported significantly lower humoral immune responses (as demonstrated by decreased titers to Newcastle disease virus). Depressed humoral and cell-mediated immune responses were also noted by Sawale et al (2009) in laying hens that had been maintained on an OTA-contaminated diet (at 1 ppm) for 60 days.…”

Section: Research Articlementioning

confidence: 99%

Immunological responses of male White Leghorn chicks kept on ochratoxin A (OTA)-contaminated feed

Hassan

Khan

Saleemi

et al. 2011

Journal of Immunotoxicology

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Experimental Mycotoxicosis in Layer Induced by Ochratoxin A and its Amelioration with Herbomineral Toxin Binder ‘Toxiroak’

Cited by 33 publications

References 25 publications

Feeding a diet contaminated with ochratoxin A for chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 1. Effects on growth and slaughter performance, haematological and serum traits

Feeding a diet contaminated with ochratoxin A for chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 1. Effects on growth and slaughter performance, haematological and serum traits

The use of Turmeric (Curcuma longa) in poultry feed

Immunological responses of male White Leghorn chicks kept on ochratoxin A (OTA)-contaminated feed

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