Experimental and Monte Carlo investigation of visible diffuse-reflectance imaging sensitivity to diffusing particle size changes in an optical model of a bladder wall

Two-Stage Analysis on Models for Quantitative Differentiation of Early-Pathological Bladder States

“…Such information is useful for noninvasive detection and interpretation of the light signals, obtained on the tissue surface. Previously described techniques [4,5] for analysis of the DR light distributions, based on the irradiation of a tissue by a narrow collimated coherent laser beam and collection of a surface backscattered nonpolarized light signal by a photodetector, showed that such an approach allows for detecting differences in light signals according to the optical properties tissues and tissue phantoms and can be applied in vivo for internal organs, such as urinary bladder (UB). This principle will be used in our study.…”