Exopolysaccharide from Lactobacillus planterum LP6: Antioxidation and the effect on oxidative stress

Li, Jingyan; Jin, Man-Man; Meng, Jianghong; Gao, Shuming; Lu, Rongrong

doi:10.1016/j.carbpol.2013.07.027

Cited by 78 publications

(38 citation statements)

References 22 publications

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“…As can be seen from figure 3, the radical scavenging activity of EPS from L. casei CO1 increases depending on the concentration of the investigated EPS: % of the radical scavenging activity (RSA) was at a concentration of EPS 2 mg/ml 17.7%; at 3 mg / ml 24% and at 4 mg / ml 26%. Excessive production of free radicals leads to oxidative damage to biomolecules (lipids, proteins, DNA), resulting in many chronic diseases, such as atherosclerosis, cancer, diabetes, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation of organs, stroke and septic shock, aging and other diseases [26]. In Zouaoui Benattouche et al notes shows that when studying the activity of EPS from S. thermophilus, the highest antioxidant activity of 55.83% was observed with the concentration of PES 1000 g/ml [27].…”

Section: 346-tetra-o-acetyl-1-o-(2-chloro-3-phenyl Thio Propyl)-βmentioning

confidence: 99%

Value of Molecular Genetic Markers in the Prognosis of Locally Advanced Forms of Cervical Cancer

Karimova

2019

GBSSJAR

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The following article reviews women's problems in Georgia and the attitude of society toward the subject. Due to the fact, that country tries to develop into a European state with worthy European values, there still is a huge problem in gender issues. Thus, it is clear that Gender politics is one of the main and essential indicators for the country's democratic development. Many non-government organizations and other social bodies are working on the problem; they have gradually introduced gender equality into the political discourse and placed it on the list of required reforms. However, along with many other emerging social problems and political tensions, this issue has not yet paid any closer attention. It is crucial to realize that without gender equality we cannot succeed as a democratic-developed country -because there is no democracy without gender equality.

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Section: 346-tetra-o-acetyl-1-o-(2-chloro-3-phenyl Thio Propyl)-βmentioning

confidence: 99%

Value of Molecular Genetic Markers in the Prognosis of Locally Advanced Forms of Cervical Cancer

Karimova

2019

GBSSJAR

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“…Moreover, they act as synergists and interact with the binding of free radicals [48]. Tsiapali et al stated that antiradical activity depends on the monosaccharide composition and glycosidic bonds [49].…”

Section: Analysis Of the Monosaccharide Composition Of The Exopolysacmentioning

confidence: 99%

Production of Exopolysaccharide by Lactobacillus Plantarum Eb-2 Strain.

Elova¹,

Kutliyeva²,

Siddikova³

et al. 2019

Theoretical & Applied Science

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An exopolysaccharide (EPS) in the amount of 250 mg/l was obtained from the culture supernatant of Lactobacillus plantarum EB-2 grown in MRS broth. In the IR spectrum of EPS, intense absorption bands were found, generally characteristic of a class of carbohydrates. The molecular weight of the EPS obtained from L.plantarum EB-2 was 3.16x10 4 Da, the polydispersity index was 1.9. The EPS from L.plantarum EB-2 consisted from a mannose, glucose, galactose and rhamnose in an molare ratio of 21.7:12.4:2:1, respectively. An in vitro study of the antioxidant activity of L.plantarum EB-2 EPS in the diphenylpicrylhydrazil (DPPH) system showed that radical scavenging activity (RSA) has being increased depending on the concentration of the investigated EPS. The maximum RSA was detected at 4 mg/ml being 42%, which is more than the activity of ascorbic acid.

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“…[ 5 6 ] EPS, especially produced by fungus, has been focused due to the fact that they not only have good rheological properties, but also possess some biological activities such as antitumor, antioxidant, anti-inflammation, immunostimulating, antianemics, and so on, which make them have potential applications in the fields of heath products and drugs. [ 7 ]…”

Section: Introductionmentioning

confidence: 99%

Preparation and bioactivity of exopolysaccharide from an endophytic fungus Chaetomium sp. of the medicinal plant gynostemma pentaphylla

Zhang¹,

Wang²,

Li³

et al. 2017

Phcog Mag

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Background:Many exopolysaccharides from the endophytes in medicinal plants possess various potential bioactivities.Materials and Methods:The endophytic fungus JY25 was isolated from the leave of the Chinese medicinal plant Gynostemma pentaphylla and identified as Chaetomium sp. by its phylogenetic and physiological analysis. One exopolysaccharide (EPS) fraction was isolated from the fermentation broth by ethanol precipitation and purified by gel filtration chromatography on Sepharose CL-6B. The molecular characteristics were examined by GC-MS, FT-IR, and multiangle laser light scattering (MALLS).Results:The monosaccharide composition analysis indicated that the purified EPS was mainly composed of glucose, mannose, arabinose, and galactose with the molecular ratio of 78.29: 8.99: 8.64: 4.08. FT-IR spectral analysis of the purified EPS revealed prominent characteristic groups, such as carbonyl bond, pyranose ring, and so on. The weight-average molar mass and the polydispersity ratio of the EPS were revealed to be 1.961×104 g/mol and 1.838, respectively. Furthermore, thermo gravimetric analysis (TGA) indicated that the degradation temperature of the purified EPS was 305° C. The purified EPS from the endophytic fungus Chaetomium sp. displayed antioxidant and antiproliferative activities.Conclusion:The results demonstrated that the EPS could be used as a healthful food and material source in pharmaceutical industries.SUMMARY An exopolysaccharides (EPS) with antioxidant and antiproliferative activities from an endophytic fungus Chaetomium sp. was reported. Abbreviations used: ANOVA: Analysis of variance; DPPH: 2,2-diphenyl-1-picrylhydrazyl; EPS: Exopolysaccharide; FT-IR: Fourier transform infrared spectroscopy; GC-MS: Gas chromatography–mass spectrometry; Mw: Mass weight; MALLS: Multiangle laser light scattering; SEC: Size Exclusion Chomatography; SPSS: Statistical Package of the Social Science; TGA: Thermo gravimetric analysis; TFA: Trifluoroacetic acid.

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Exopolysaccharide from Lactobacillus planterum LP6: Antioxidation and the effect on oxidative stress

Cited by 78 publications

References 22 publications

Value of Molecular Genetic Markers in the Prognosis of Locally Advanced Forms of Cervical Cancer

Value of Molecular Genetic Markers in the Prognosis of Locally Advanced Forms of Cervical Cancer

Production of Exopolysaccharide by Lactobacillus Plantarum Eb-2 Strain.

Preparation and bioactivity of exopolysaccharide from an endophytic fungus Chaetomium sp. of the medicinal plant gynostemma pentaphylla

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