Exfoliation syndrome angle characteristics: a lack of correlation with amount of disc damage

Prevalence and Early Detection of Abdominal Aortic Aneurysm in Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma

“…No differences in neuro-retinal rim area, area of peri-papillary atrophy, rim-to-disc ratio, and cup area were found between PEXS and PEXG eyes, or between POAG and cataract eyes. 26 Eyes with PEX have greater anterior chamber angle pigmentation than do non-glaucomatous eyes. The elevation of intraocular pressure and greater angle pigmentation seem to correlate well.…”

Correlation of Capsular Pseudoexfoliation Material and Iridocorneal Angle Pigment With the Severity of Pseudoexfoliation Glaucoma

“…Other investigators, however, found no correlation between the trabecular meshwork pigmentation and the severity of glaucoma. 1,16,17 Our study has some limitations. The grading systems used for PXF material and pigment may not truly represent the amount of these deposits present in the outflow pathway.…”

“…[1][2][3][4][5] The diagnosis of PXF glaucoma is made clinically by establishing the presence of glaucomatous optic disc changes and/or visual field defects in the presence of PXF material in the anterior segment of the eye. 2,3,6 Histopathologically, PXF material consists of mucopolysaccharide-containing fibrils elaborated by the lens epithelium, endothelium of Schlemm canal, and corneal endothelium.…”

Evaluation of the anterior chamber angle in pseudoexfoliation syndrome

“…26 On the other hand, it is not known whether the degree of angle pigmentation and the amount of EXM correlates with the severity of glaucoma. 27 Shuba et al presented a positive correlation between pigmentation of the angle and IOP (p = 0.047) and no correlation with the severity of glaucoma (p > 0.13). There was no significant correlation between the amount of EXM and the level of IOP, nor a correlation with glaucoma severity indicators (p > 0.04).…”

“…This finding confirms that the Sampaolesi line is associated with the presence of pseudoexfoliation syndrome, but does not determine the presence of glaucoma. 27 PEXG is classified as secondary open-angle glaucoma. However, a higher incidence of narrow-or closed-angle glaucoma in patients with PEX was reported: 18% of patients had narrow-angle, 14% had closed-angle, and 37.83% of patients had angle closure.…”