“…Hence, in order to maintain the first web space, avoid adduction deformity, and improve thumb stability, it is recommended to strengthen the thumb extensors and abductors as well as the wrist extensor muscles. Many authors further claim that excessive exercises to improve pinch or key grip strength should be avoided, as these, especially in later phases of CMC1 OA, may result in increased subluxation and pain in instable joints (31)(32)(33)(34). Concern is also expressed regarding exercises aimed at reaching full flexion and opposition of the thumb, since the motion gained by this exercise may be of no functional benefit to the patient if the increased ROM results in a painful motion (34).…”