Excellent Hemodynamic Performance After Aortic Valve Neocuspidization Using Autologous Pericardium

Krane, Markus; Boehm, Johannes; Prinzing, Anatol; Ziegelmueller, Johannes; Holfeld, Johannes; Lange, Rüdiger

doi:10.1016/j.athoracsur.2020.04.108

Cited by 42 publications

(56 citation statements)

References 19 publications

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“…In another study conducted on 77 patients who mostly had AS, Krane et al, reported that moderate-severe AI was developed in 2 patients. In the same study, they denoted that the hospitalization times were similar to those of prosthetic AVR patients [22]. Also, studies that compared AVNeo with the aortic valve replacement reported that greater effective aortic valve area and smaller aortic valve pressure gradient pressure were obtained with AVNeo procedure [23] [24].…”

Section: Discussionmentioning

confidence: 86%

Aortic Neocuspidization with Autologous Pericardium: Initial Experience of Single Center

Karabacak¹,

Kubat²,

Erol³

et al. 2021

WJCS

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Background: Aortic neo-cuspidization (AVNeo) procedure has been adopted by limited centers with the publication of the mid-long term successful results. The aim of this study was to present initial experience of the AVNeo procedure of a single center. Methods: The medical records of 24 patients who underwent AVNeo with or without concomitant cardiac surgery between February 2019 and February 2021 at our tertiary hospital were scanned retrospectively. Results: The mean age of patients was aged 58.21 ± 13.14 years and 16 (66.7%) of them were men. 16 patients were operated on for aortic stenosis (66.67%). Morphology of the aortic valve was tricuspid in 21 (87.5%) and bicuspid in 3 (12.5%) of the patients. Additional cardicac surgery was performed in 13 (54.17%) patients. No patients needed reoperation for bleeding, pacemaker implantations, conversion to classical prosthetic aortic valve replacement, or infective endocarditis. Two patients died due to non-cardiac reasons. Preoperative peak and mean aortic valve pressures improved significantly at 1 st and 6 th months (

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Section: Discussionmentioning

confidence: 86%

Aortic Neocuspidization with Autologous Pericardium: Initial Experience of Single Center

Karabacak¹,

Kubat²,

Erol³

et al. 2021

WJCS

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“…Ozaki et al revealed that no conversion to valve replacement in all 850 aortic reconstructed patients [23]. Of 103 patients had Ozaki's technique, there were 2 patients required to convert into replacing prosthetic valve due to occlusion of left coronary artery caused by left cusp according to Krane et al [27]. Therefore, the measurement of distance among 2 commissures should be ensured to be stable and tight, which prevents cusps s from being oversized.…”

Section: Discussionmentioning

confidence: 99%

Initial results of aortic valve reconstruction using autologous pericardium (Ozaki's procedure)

Hung¹,

Huu²,

Nguyên³

et al. 2021

VJCTS

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Introduction: This study report the clinical characteristics, surgical indications, surgical technique and initial outcomes of autologous pericardial aortic valve reconstruction using Ozaki’s procedure. Methods: The study included consecutive patients with isolated aortic valve disease who underwent Ozaki’s procedure between June 2017 and December 2019. Aortic valve cups were reconstructed by autologous pericardium using Ozaki’s procedure. Results: Seventy-two patients were enrolled (mean age 52.9 ± 13 years; 53 males) and consisted of 30 aortic stenosis cases, 20 aortic regurgitation cases, and 22 patients with a combination of both 72 patients, a bicuspid aortic valve was present in 20, and 7 patients had infective endocarditis. Surgery was performed via a full or partial sternotomy. The procedure was successful in 70 case, and two patients were converted to prosthetic valve replacement. The aortic cross-clamp time was 106.3 ± 13.8 minutes, cardiopulmonary bypass time was 136.7 ± 18.5 minutes. One patient died of cardiac tamponade in hospital, and two patients underwent reoperation due to bleeding and sternal infection, respectively, were observed during the follow-up period of 30 days. 1-month postoperative echocardiography revealed that one patient had moderate aortic valve regurgitation, max trans-valvular pressure gradient was 16.1 ± 2.3 mmHg, and aortic valve area was 2.5 ± 0.2 cm ². Conclusions: Aortic valve reconstruction using autologous pericardium by Ozaki’s procedure was feasible, good hemodynamics, and can be applied to all lesions of the aortic valve.

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“…Other authors (Ozaki et al 11 and Krane et al 17 ) performed aortic valve reconstruction in cases of both isolated aortic valve disease and in combination with other surgeries such as coronary artery bypass graft (CABG), mitral valve repair or replacement. Nevertheless, our study enrolled only patients with isolated aortic valve disease because (1) With a new technique, the selection of isolated AVD would reduce surgical and aortic cross-clamp time; (2) Outcomes evaluation would not be influenced by various factors.…”

Section: Indications Of Aortic Valve Reconstruction Surgery By Ozaki Proceduresmentioning

confidence: 99%

Aortic Valve Reconstruction Surgery Using Autologous Pericardium: The Experience in Vietnam

Ngo¹,

Nguyen²,

Thinh³

et al. 2021

Preprint

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Objective: The study aimed to evaluate the indications and describe the aortic valve reconstruction techniques by Ozaki’s procedure in Vietnam and report mid-term outcomes of this technique in Vietnam. Methods: Between June 2017 and December 2019, 72 patients diagnosed with isolated aortic valve disease, with a mean age of 52.9 (19 – 79 years old), and a male:female ratio of 3:1 underwent aortic valve reconstruction surgery by Ozaki’s technique at Cardiovascular Center, E Hospital, Vietnam. Results: The aortic valve diseases consisted of aortic stenosis (42%), aortic regurgitation (28%), and a combination of both (30%). In addition, the proportion of aortic valves with bicuspid morphology and small annulus (≤ 21 mm) was 28% and 38.9%, respectively. The mean aortic cross-clamp time was 106 ± 13.8 minutes, mean cardiopulmonary bypass time was 136.7 ± 18.5 minutes, and 2.8% of all patients required conversion to prosthetic valve replacement surgery. The mean follow-up time was 26.4 months (12- 42 months), the survival rate was 95.8%, the reoperation rate was 2.8%, and rate of postoperative moderate or higher aortic valve regurgitation was 4.2%. Postoperative valvular hemodynamics was favorable, with a peak pressure gradient of 16.1 mmHg and an effective orifice area index of 2.3 cm . Conclusions: This procedure was safe and effective, with favorable valvular hemodynamics and a low rate of valvular degeneration. However, more long-term follow-up data are needed.

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Excellent Hemodynamic Performance After Aortic Valve Neocuspidization Using Autologous Pericardium

Cited by 42 publications

References 19 publications

Aortic Neocuspidization with Autologous Pericardium: Initial Experience of Single Center

Aortic Neocuspidization with Autologous Pericardium: Initial Experience of Single Center

Initial results of aortic valve reconstruction using autologous pericardium (Ozaki's procedure)

Aortic Valve Reconstruction Surgery Using Autologous Pericardium: The Experience in Vietnam

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