Examination of the Phenolic Profile and Antioxidant Activity of the Leaves of the Australian Native Plant <i>Smilax glyciphylla</i>

Huang, Ancheng C.; Wilde, Amelie Sina; Ebmeyer, Johanna; Skouroumounis, George K.; Taylor, Dennis K.

doi:10.1021/np4005163

Cited by 17 publications

(17 citation statements)

References 21 publications

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“…(Hamamelidaceae) (Iwashina et al 2012), Hovenia Lignum (An et al 2007), Ziziphus spp. (Rhamnaceae)(Pawlowska et al 2009), Smilax glyciphylla (Smilaceae)(Huang et al 2013), Fagopyrum esculentum (Polygonaceae)(Nagatomo et al 2014) and Aspalathuslinearis…”

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Health effects of phloretin: from chemistry to medicine

et al. 2017

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Dihydrochalcones are a class of secondary metabolites, whose demand in biological and pharmacological applications is rapidly growing. Phloretin is one of the best known and abundant dihydrochalcone characterized by the presence of 2,6-dihydroxyacetophenone pharmacophore. It is a versatile molecule with anticancer, antiosteoclastogenic, antifungal, antiviral, anti-inflammatory, antibacterial and estrogenic activities and able to increase the fluidity of biological membranes and penetration of administered drugs. In this review we have performed a critical evaluation of available literature as far as phloretin beneficial effects and activation/block of intracellular signal cascade are of concern. In addition, we supply useful information on its chemical properties, sources and bioavailability.

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Health effects of phloretin: from chemistry to medicine

et al. 2017

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“…The antioxidant activity of pure compounds was evaluated using ferric reducing ability of plasma (FRAP) and DPPH • radical scavenging. The flavonoids showed a good antioxidant activity; contrary to this, the dihydrochalcones showed weak antioxidant activity [50].…”

Section: Smilax Glycyphyllamentioning

confidence: 86%

“…Huang et al performed a study of phenolic profile and antioxidant activity of S. glycyphylla leaves [50]. The leaves of S. glycyphylla previously dried and blended were extracted with 80% aqueous ethanol.…”

Section: Smilax Glycyphyllamentioning

confidence: 99%

Phenolic Compounds in Genus Smilax (Sarsaparilla)

Salas-Coronado¹,

Hernández-Carlos²,

Llaguno-GuilbertoJoseoziel³

et al. 2017

Phenolic Compounds - Natural Sources, Importance and Applications

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Smilax (Smilacaceae) is a genus of about 350 species, found in temperate, tropical and subtropical zones worldwide. The plants belonging to this genus are found throughout Asia, Europe, Oceania and the Americas. Species of the genus Smilax commonly called sarsaparilla are characterized as climbers, with long, thin thorny stem. The branches have tendrils which attach to other plants or objects and grow steadily upward. The roots of these plants have been used for centuries in Asia and the Americas as a tonic, diuretic and sudorific. The rhizome, roots, stems and leaves of sarsaparilla are used in traditional medicine. In the scientific literature, there are several reports on immunomodulatory properties, anticonvulsant, antibacterial, antifungal, anticancer, antidiabetic and antioxidant properties. However, there are no reports which explain the antioxidant activity of sarsaparilla extracts as a function of phenolic compound structures, such as flavonoids and phenylpropanoids. In this chapter, the relevance of phenolic chemical structure in antioxidant and anticancer activity of sarsaparilla extracts will be described. Special emphasis is placed on phenylpropanoid glycosides that consist of a sucrose core. These compounds are evidence of chemotaxonomy in the genus Smilax.

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“…The FRAP assay performed was slight modified according to the previous reported literature252627. The FRAP reagent was freshly prepared by adding 3 M CH 3 COOH buffer (pH 3.6), 0.1 M 2,4,6-Tris(2-pyridyl)-s-triazine and 0.2 M FeCl3 at 10:1:1 volume ratio in 0.4 M HCl.…”

Section: Methodsmentioning

confidence: 99%

Antioxidative Polyketones from the Mangrove-Derived Fungus Ascomycota sp. SK2YWS-L

Tan

Liu

Chen

et al. 2016

Sci Rep

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Three novel 2,3-diaryl indone derivatives, ascomindones A−C (1−3), and two new isobenzofuran derivatives, ascomfurans A (4) and B (5), together with four know compounds (6−9) were isolated from the culture of a mangrove-derived fungus Ascomycota sp. SK2YWS-L. Their structures were elucidated on the interpretation of spectroscopic data. 1 and 4 were further constructed by analysis of X-ray diffraction. Antioxidant properties based on 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl radical scavenging activities and the ferric reducing ability power (FRAP) of the new compounds were assayed. All of them exhibited significant effects, of which 1 showed more potent activity than ascorbic acid in scavenging DPPH radical with IC50 value of 18.1 μM.

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Examination of the Phenolic Profile and Antioxidant Activity of the Leaves of the Australian Native Plant Smilax glyciphylla

Cited by 17 publications

References 21 publications

Health effects of phloretin: from chemistry to medicine

Health effects of phloretin: from chemistry to medicine

Phenolic Compounds in Genus Smilax (Sarsaparilla)

Antioxidative Polyketones from the Mangrove-Derived Fungus Ascomycota sp. SK2YWS-L

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