Evidence for an immunocompromising effect of bovine pestivirus on bovid herpesvirus 1 vaccination

Edwards, S.; Wood, L; Hewitt-Taylor, C.; Drew, Trevor W.

doi:10.1007/bf02213992

Cited by 27 publications

(10 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some of these diseases, such as bovine viral diarrhoea (BVD), are known to induce immunosuppression (Ketelsen et al, 1979;Roth et al, 1981;Bolin et al, 1985;Markham and Ramnaraine, 1985;Roth et al, 1986). This could impair the immune response to vaccination (Edwards et al, 1986). Calves revaccinated against FMD during this period of immunosuppression may not respond normally to the vaccination.…”

Section: Discussionmentioning

confidence: 99%

Serological response to a booster foot-and-mouth disease vaccination with strains different from the primary vaccine

Clercq¹,

Strobbe²,

Vanopdenbosch³

et al. 1989

Vet Res Commun

View full text Add to dashboard Cite

Young calves were vaccinated with belgian foot-and-mouth disease (FMD) vaccine and revaccinated with either the same vaccine or with a foreign FMD vaccine. There was a significant serological response to the primary vaccine strains after the first vaccination which was greater following revaccination. At one and two months after revaccination there was no significant difference between the responses to revaccination with vaccine identical to the primary vaccine or with the foreign FMD vaccine. It was concluded that revaccination of young calves is effective even with an FMD vaccine different from the primary vaccine.

show abstract

Section: Discussionmentioning

confidence: 99%

Serological response to a booster foot-and-mouth disease vaccination with strains different from the primary vaccine

Clercq¹,

Strobbe²,

Vanopdenbosch³

et al. 1989

Vet Res Commun

View full text Add to dashboard Cite

show abstract

“…Furthermore, infection with BVDV may lead to enhanced virulence and pathogenesis of secondary infections [103]. Experiments in bovine calves have shown that animals previously infected with BVDV are less effective at containing infection with BHV-1 and present with more severe clinical signs, and presence of BHV-1 favours BVDV persistence [104][105][106]. If similar processes occur in Rangifer, this could explain the observed pattern.…”

Section: Alphaherpesvirus and Pestivirusmentioning

confidence: 94%

Multi-pathogen serological survey of migratory caribou herds: A snapshot in time

et al. 2019

View full text Add to dashboard Cite

Pathogens can impact host survival, fecundity, and population dynamics even when no obvious disease is observed. Few baseline data on pathogen prevalence and diversity of caribou are available, which hampers our ability to track changes over time and evaluate impacts on caribou health. Archived blood samples collected from ten migratory caribou herds in Canada and two in Greenland were used to test for exposure to pathogens that have the potential to effect population productivity, are zoonotic or are emerging. Relationships between seroprevalence and individual, population, and other health parameters were also examined. For adult caribou, the highest overall seroprevalence was for alphaherpesvirus (49%, n = 722), pestivirus (49%, n = 572) and Neospora caninum (27%, n = 452). Lower seroprevalence was found for parainfluenza virus type 3 (9%, n = 708), Brucella suis (2%, n = 758), and Toxoplasma gondii (2%, n = 706). No animal tested positive for antibodies against West Nile virus (n = 418) or bovine respiratory syncytial virus (n = 417). This extensive multi-pathogen survey of migratory caribou herds provides evidence that caribou are exposed to pathogens that may have impacts on herd health and revealed potential interactions between pathogens as well as geographical differences in pathogen exposure that could be linked to the bio-geographical history of caribou. Caribou are a keystone species and the socioeconomic cornerstone of many indigenous cultures across the North. The results from this study highlight the urgent need for a better understanding of pathogen diversity and the impact of pathogens on caribou health.

show abstract

“…Experimental studies found that acute infections with BVDv enhanced susceptibility to infection with bovine herpes virus 1, 11 and case reports have linked concurrent infections with other BRDC-associated pathogens with BVDv infections. 12 Subsequent experimental studies showed healthy cattle exposed to BVDv responded differently to a challenge with Mannheimia haemolytica than calves not previously exposed to BVDv.…”

Section: Immunosuppression Associated With Bovine Viral Diarrhea Virumentioning

confidence: 99%

Bovine Viral Diarrhea Virus–Associated Disease in Feedlot Cattle

Larson

2015

Veterinary Clinics of North America: Food Animal Practice

View full text Add to dashboard Cite

Bovine viral diarrhea virus (BVDv) is associated with bovine respiratory disease complex and other diseases of feedlot cattle. Although occasionally a primary pathogen, BVDv's impact on cattle health is through the immunosuppressive effects of the virus and its synergism with other pathogens. The simple presence or absence of BVDv does not result in consistent health outcomes because BVDv is only one of many risk factors that contribute to disease syndromes. Current interventions have limitations and the optimum strategy for their uses to limit the health, production, and economic costs associated with BVDv have to be carefully considered for optimum cost-effectiveness.

show abstract

Evidence for an immunocompromising effect of bovine pestivirus on bovid herpesvirus 1 vaccination

Cited by 27 publications

References 3 publications

Serological response to a booster foot-and-mouth disease vaccination with strains different from the primary vaccine

Serological response to a booster foot-and-mouth disease vaccination with strains different from the primary vaccine

Multi-pathogen serological survey of migratory caribou herds: A snapshot in time

Bovine Viral Diarrhea Virus–Associated Disease in Feedlot Cattle

Contact Info

Product

Resources

About