EVerT: cryotherapy versus salicylic acid for the treatment of verrucae – a randomised controlled trial.

Abstract

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A comparative study between intralesional PPD and vitamin D3 in treatment of viral warts

“…All of these treatments are essentially painful, time consuming, expensive and recurrence is common. [1][2][3][4][5][6] Therefore immunotherapy seems to be a promising modality in such cases. The role of immunity is documented by the appearance and persistence of warts in immunosuppressed individuals.…”

Scoping systematic review of treatments for eczema

“…Theoretically, one could argue that they are established treatments and so do not require evaluation. Yet history suggests, through various examples (such as the universal use of cryotherapy for plantar warts, which is no better than topical salicylic acid 448 ), that simple widespread use of a mode of therapy may be a weak defence for an evaluation bypass. This is not to suggest that universal treatments such as emollients should be stopped or restricted on the basis of a lack of RCT evidence, as this would limit patient choice and paradoxically favour the use of powerful treatments such as ciclosporin that have been evaluated thoroughly by RCTs.…”

Natural Course of Cutaneous Warts Among Primary Schoolchildren: A Prospective Cohort Study

“…6 Less potent over-the-counter (OTC) cryotherapy or salicylic acid (usually 17%) treatments are offered in pharmacies without a prescription. 7 Because warts resolve spontaneously and available treatments often fail, especially in the case of plantar warts, [8][9][10] a wait-and-see policy may be considered in treatment decisions. 11 Studies on the natural course of warts are scarce and outdated, however.…”