Evaluation of wound healing activity of root of Mimosa pudica

“…The wounding day was considered as day 0. When wounds were cured thoroughly, the sutures were removed on the 8th post-wounding day and the tensile strength of the skin that is the weight in grams required to break open the wound/skin was measured by tensiometer on the 10th day reported (Mohammed, 2006;Dnyaneshwar et al, 2009;Sachin et al, 2009;Kiran and Asad, 2008;Zhaia et al, 2009). …”

Section: Incision Wound Modelmentioning

confidence: 99%

EXPLORATION OF HEALING PROMOTING POTENTIALS OF LEAVES OF <i>MORUS ALBA</i> L. IN ALBINO RATS

Kaushik¹

2013

American Journal of Pharmacology and Toxicology

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To establish the wound healing activity of aqueous and ethanolic extract of roots of Morus alba. Two models were performed to evaluate the wound healing activity i.e., Incision and Excision model. In incision model the parameter which was carried out was breaking strength of wounded skin. In excision model percentage wound contraction and period of epithelialization was established for both the extracts. Reference standard drug was Aloe vera ointment for comparison with other groups. From the observation in both the models, Aq. extract of Morus alba was found to have greater wound healing activity in terms of breaking strength in incision model and percentage wound contraction, period of epithelialization was highest in excision model compared with other groups. In conclusion, our findings suggest that aq. extract of Morus alba possess better healing ability than the ethanolic extract.

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“…5 The most important biologically active constituents of this plants are alkaloids, steroids, tannins, flavonoids, glycosides and saponins compounds. 6 The wide range of pharmacological activities of this plant have been reported including wound healing, 7,8 analgesic, anti-inflammatory, 9 anticonvulsant, 10 anti-diarrhea, 6,11 anti-oxidant, 5,9,12,13 hepatoprotective, 13,14 hypolipidemic, 15,16 diuretic property, 17 hypoglycemic 5,[18][19][20] and hyperglycemia activities. 21 A. indicum Sweet is belonging to the family Malvaceae.…”

Section: Introductionmentioning

confidence: 99%

Effect of Thai Folklore Recipe from Abutilon indicum and Mimosa pudica in Streptozotocin-Induced Diabetic Rats

Konsue¹,

Talubmook²

2018

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Context:Abutilon indicum and Mimosa pudica were a folklore recipe in Northeastern of Thailand. The recipe was reported that claim to diabetic treatment. Aims: The studies were evaluated to hypoglycemic effect, serum insulin secretion and blood biochemistry in streptozotocin (STZ)-induced diabetic rats. Materials and Methods: The recipe were composed of whole plants from A. indicum and M. Pudica (1:1 w/w) powder. The pound plants were macerated with aqueous (AMA), hydro-ethanol (AMHE) and 80% ethanol (AME) to crude extracts. The AMA, AMHE and AME at the doses of 125, 250 and 500 mg/kg body weight (b.w.) were administered orally daily in diabetic rats during eight weeks. Fasting blood glucose levels (FBG) were measured at weekly. The serum insulin levels and blood biochemical data including blood urea nitrogen (BUN), creatinine (CREA), total protein (TP), albumin (Alb), serum aspartate aminotransferase (AST), serum alanine aminotransferase (ALT), alkaline phosphatase (ALP), triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) were estimated at the end of experiment. Results: All doses of the extracts were showed significantly (p<0.05) decreasing percent age of FBG in diabetic rats. Especially, AME 125 mg/ kg b.w. was showed more potent significantly (p<0.05) decreasing percentage of FBG at week of 2, 5, 7 and 8. The serum insulin levels of all doses administered with the extracts were significantly (p< 0.05) higher than diabetic control group. On the other hand, all doses of the extracts were significantly (p< 0.05) decreasing ALT and ALP lower than diabetic control group. While, AMA and AMHE at the doses of 250 and 500 mg/kg b.w. were increased HDL, but decreased TC, TG and LDL. Conclusion: The study was proved to diabetic treatment and improvement of diabetic stage and blood biochemical parameters. In addition, the experiment was confirmed to folklore traditional use.

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Evaluation of wound healing activity of root of Mimosa pudica

Cited by 160 publications

References 11 publications

Enhancement of wound healing with roots of Ficus racemosa L. in albino rats

Enhancement of wound healing with roots of Ficus racemosa L. in albino rats

EXPLORATION OF HEALING PROMOTING POTENTIALS OF LEAVES OF <i>MORUS ALBA</i> L. IN ALBINO RATS

Effect of Thai Folklore Recipe from Abutilon indicum and Mimosa pudica in Streptozotocin-Induced Diabetic Rats

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