2016
DOI: 10.7324/japs.2016.60918
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Evaluation of total phenolic content and antioxidant activity of different solvent extracts of leaf material of Spathodea campanulata P. Beauv. and investigation of their proliferation inhibition potential against EAC cell line

Abstract: In the present study, antioxidant and anticancer activities of different solvent extracts of an Indian medicinal plant, Spathodea campanulata P. Beauv. (leaf) were investigated. Among the different extracts studied, 70% ethanolic extract of S. campanulata leaf registered high antioxidant activity in terms of phosphomolybdate reducing power (955 FAEA), radical scavenging activity against DPPH (84.67%), superoxide (72.69%), hydrogen peroxide (83.20%) and hydroxyl radicals (70%), when compared to ethyl acetate an… Show more

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Cited by 7 publications
(8 citation statements)
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“…The presence of tannins in the leaf extract could be the basis to the therapeutic use of the leaf as an antidote to animal poisoning and antioxidant. Onah [12] also revealed that methanol leaf extract of S. companulata showed antioxidant property, other researchers also reported that methanol(polar) extract has a high effectiveness as antioxidants, with these reports it is not surprising that the plant is used as an antioxidant [8,12,16,17,33,34]. The absence of flavonoids in the methanol extract is in line with report of Pulipati et al [11] that methanol leaf extract of S. companulata contained no flavonoids.…”
Section: Resultssupporting
confidence: 73%
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“…The presence of tannins in the leaf extract could be the basis to the therapeutic use of the leaf as an antidote to animal poisoning and antioxidant. Onah [12] also revealed that methanol leaf extract of S. companulata showed antioxidant property, other researchers also reported that methanol(polar) extract has a high effectiveness as antioxidants, with these reports it is not surprising that the plant is used as an antioxidant [8,12,16,17,33,34]. The absence of flavonoids in the methanol extract is in line with report of Pulipati et al [11] that methanol leaf extract of S. companulata contained no flavonoids.…”
Section: Resultssupporting
confidence: 73%
“…The ethylacetate leaf extract contained flavonoids, tannins and glycosides. The presence of tannins and flavonoids showed the basis of ethnomedicinal use of the leaf as antioxidant since flavonoids and tannins were reported to have shown high antioxidant activities [16,40,41,42]. Alkaloids, saponins, flavonoids, glycosides were present in the ethyl acetate stem extract.…”
Section: Resultsmentioning
confidence: 99%
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“…[ 14 ] Besides this, SRA has been reported to act as a chemotherapeutic and chemopreventive both in vitro and in vivo. [ 15,16 ]…”
Section: Introductionmentioning
confidence: 99%
“…[14] Besides this, SRA has been reported to act as a chemotherapeutic and chemopreventive both in vitro and in vivo. [15,16] The present work is done aiming to explore the anticancer effect of SRA in oral cancer SCC131 cell lines and to identify the me-…”
mentioning
confidence: 99%