“…However, there are still limitations to the solubility and stability of curcumin although many methods such as liposome 45 , polymeric nanoparticles 46 , solid lipid nanoparticles (SLNs) 47 , albumin nanoparticles 48 , microemulsions and nanoemulsions 49 , nanospheres, and microcapsules 50 have been devised in recent years to obtain a higher aqueous solubility, bioavailability, activity, and lower toxicity 28,51 . In this regard, the emulsion method has received much attention in recent decades due to containing a simple synthesizing process and high efficiency, as well as requiring low costs, and eco-friendly materials [52][53][54][55][56] . This method has been exerted to synthesize water-insoluble substances 57,58 , oils 59,60 , plant extracts 61,62 , proteins 63 , nucleic acids 64 , curcumin, and many other substances 49 for drug delivery intentions, while some of these materials have been evaluated even in nanofiber scaffolds [65][66][67] .…”