Evaluation of the mass of bacterial excretion in patients with tuberculosis and combined pathology (HIV infection and tuberculosis)

Abstract

A comparative assessment of the frequency and massiveness of Mycobacterium tuberculosis isolation in patients with tuberculosis and patients with combined pathology (HIV infection and tuberculosis) is presented. It was found that the frequency of mycobacteria isolation by PCR and bacteriological methods did not significantly differ from each other, but was significantly higher than with bacterioscopy. The frequency of mycobacteria isolation in patients with combined infections (HIV and tuberculosis) and monoinfection (tuberculosis) was equal. At the same time, patients with combined pathology were significantly less likely to have massive bacterial excretion compared to monoinfection with tuberculosis, and significantly more likely to have poor bacterial excretion. Patients with co-infection with HIV and tuberculosis are less dangerous as sources of tuberculosis infection for others, especially in homes, medical and social organizations. The identified features can be used in the organization of anti-epidemic measures in foci.