Evaluation of the genotoxic effects of formocresol application in vital pulp therapy of primary teeth: a clinical study and meta-analysis

Filho, Arnoldo Vasconcelos de Alencar; Santos, Valdeci Elias dos; Calixto, Merilane da Silva; Santos, Neide; Heimer, Mônica Vilela; Rosenblatt, Aronita

doi:10.1007/s00784-018-2352-y

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…When pulpectomy is performed in multiple sessions, calcium hydroxide is the most widely used material as intracanal medication, 15 which is consistent with our results. Despite a study evaluating the mutagenic effect of formocresol 16 and its classification as a carcinogenic by the International Agency for Research on Cancer, we found that a considerable number of faculty members still recommend its use, which is in agreement with the data described in Bergoli et al 1 and Hincapié et al 2 A review addressing pulpectomy for primary teeth concluded that, while formocresol is effective, there are concerns regarding its toxicity. 5 As there are well-founded concerns and risks, biocompatible materials are preferred for use on primary teeth.…”

Section: Discussionsupporting

confidence: 87%

Teaching pulpectomy in paediatric dentistry: A national cross‐sectional survey of dental schools in Brazil

Campos,

Gois,

Serafim

et al. 2024

Int J Paed Dentistry

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BackgroundPulpectomy is used to treat primary teeth with irreversibly inflamed or necrotic pulp tissue. There is, however, a lack of consensus on clinical protocols for teaching pulpectomy at dental schools.AimTo determine what faculty members at Brazilian dental schools are teaching about pulpectomy in primary teeth.DesignA cross‐sectional, observational study was conducted using a 39‐question survey available via the Google Forms® platform. A snowball sampling strategy was used for recruitment. Invitations to participate were sent via e‐mail, WhatsApp® and Instagram®. The data were analysed descriptively.ResultsA total of 177 (58.4%) responses were obtained. Most faculty members recommended the use of Kerr hand files (66.1%), and 1% sodium hypochlorite was the most common choice for the irrigating solution (35.3%). Iodoform pastes were the first choice of faculty members (41.6%), and 60.5% of the faculty members recommended composite resin as the definitive restoration.ConclusionSimilarities were found in the teaching of pulpectomy for primary teeth among faculty members at dental schools in Brazil.

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Section: Discussionsupporting

confidence: 87%

Teaching pulpectomy in paediatric dentistry: A national cross‐sectional survey of dental schools in Brazil

Campos,

Gois,

Serafim

et al. 2024

Int J Paed Dentistry

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Clinical and radiographic comparison of Biodentine and Formocresol: an updated meta-analysis with trial sequential analysis

Firoozi

Salman

Aminabadi

2022

Eur Arch Paediatr Dent

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Comparação clínica e radiológica de pulpotomia em dentes decíduos com formocresol, MTA e biodentine

Albuquerque

Silva

et al. 2021

RSD

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Introdução: O processo de pulpotomia convencionalmente é feito com formocresol, porém, devido as suas características mutagênicas, novos materiais obturadores foram desenvolvidos como alternativa. Objetivo: Revisar a literatura de forma integrativa a respeito do material obturador mais adequado para pulpotomia de dentes decíduos. Metodologia: A busca ocorreu nas bases de dados Pubmed e Medline, por meio dos descritores: “child”, “children”, “primary teeth”, “tooth, deciduous”, “primary tooth”, "pulpotomy", "pediatric dentistry", "endodontics", "root canal filling materials", "materials", "material", "biodentine", "mineral trioxide aggregate", "formocresol", "formocresols", "cytotoxicity", "biocompatible materials", "biocompatibility", "radiopacity", "radiographic" e "radiography, dental". Foram incluídos ensaios clínicos, estudos retrospectivos e estudos prospectivos, publicados entre 2016 e 2021, em inglês ou português. Os critérios de exclusão foram teses, dissertações, monografias, cartas ao editor, livros e revisões de literatura. Resultados: A pesquisa resultou em 9 estudos de ambas as bases de dados, com maior prevalência de ensaios clínicos. Conclusão: O material mais recomendado para realização de pulpotomias em dentes decíduos é o Biodentine e Mineral Trioxide Aggregate, devendo a escolha ser feita de acordo com o critério do profissional e caso do paciente. É preciso que seja considerado os custos e colaboração do paciente durante o tratamento.

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Evaluation of the genotoxic effects of formocresol application in vital pulp therapy of primary teeth: a clinical study and meta-analysis

Abstract: This research helps to bring scientific evidence of the safe use of formocresol in deciduous pulpotomy treatments.

Cited by 3 publications

References 16 publications

Teaching pulpectomy in paediatric dentistry: A national cross‐sectional survey of dental schools in Brazil

Teaching pulpectomy in paediatric dentistry: A national cross‐sectional survey of dental schools in Brazil

Clinical and radiographic comparison of Biodentine and Formocresol: an updated meta-analysis with trial sequential analysis

Comparação clínica e radiológica de pulpotomia em dentes decíduos com formocresol, MTA e biodentine

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